node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKAP9 | C1orf87 | ENSP00000348573 | ENSP00000360244 | A-kinase anchor protein 9; Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Required to maintain the integrity of the Golgi apparatus. Recruited to the Golgi apparatus by GM130/GOLGA2 and is required for microtubule nucleation at the cis-side of the Golgi apparatus. Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. Forms a complex with PDE4DIP- the complex recruits CAMSAP2 to the Golgi apparatus, leading to tether non-centrosomal minus-end microtubules to the Golg [...] | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | 0.512 |
ALX3 | C1orf87 | ENSP00000358807 | ENSP00000360244 | Homeobox protein aristaless-like 3; Transcriptional regulator with a possible role in patterning of mesoderm during development; PRD class homeoboxes and pseudogenes | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | 0.657 |
C1orf87 | AKAP9 | ENSP00000360244 | ENSP00000348573 | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | A-kinase anchor protein 9; Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Required to maintain the integrity of the Golgi apparatus. Recruited to the Golgi apparatus by GM130/GOLGA2 and is required for microtubule nucleation at the cis-side of the Golgi apparatus. Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. Forms a complex with PDE4DIP- the complex recruits CAMSAP2 to the Golgi apparatus, leading to tether non-centrosomal minus-end microtubules to the Golg [...] | 0.512 |
C1orf87 | ALX3 | ENSP00000360244 | ENSP00000358807 | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | Homeobox protein aristaless-like 3; Transcriptional regulator with a possible role in patterning of mesoderm during development; PRD class homeoboxes and pseudogenes | 0.657 |
C1orf87 | CCDC15 | ENSP00000360244 | ENSP00000341684 | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | Coiled-coil domain containing 15 | 0.522 |
C1orf87 | EEF1A1 | ENSP00000360244 | ENSP00000339063 | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily | 0.800 |
C1orf87 | LRRC2 | ENSP00000360244 | ENSP00000379241 | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | Leucine-rich repeat-containing protein 2; Leucine rich repeat containing 2 | 0.488 |
C1orf87 | MYO10 | ENSP00000360244 | ENSP00000421280 | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | Unconventional myosin-X; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. In hippocampal neurons i [...] | 0.494 |
C1orf87 | OXSM | ENSP00000360244 | ENSP00000280701 | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function; Belongs to the beta-ketoacyl-ACP synthases family | 0.509 |
C1orf87 | SNX1 | ENSP00000360244 | ENSP00000261889 | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | Sorting nexin-1; Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3- phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called e [...] | 0.538 |
C1orf87 | SRP68 | ENSP00000360244 | ENSP00000312066 | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function | 0.483 |
C1orf87 | ZBED1 | ENSP00000360244 | ENSP00000370621 | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | Zinc finger BED domain-containing protein 1; Binds to 5’-TGTCG[CT]GA[CT]A-3’ DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elements, but does not code for any transposase activity | 0.630 |
CCDC15 | C1orf87 | ENSP00000341684 | ENSP00000360244 | Coiled-coil domain containing 15 | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | 0.522 |
CCDC15 | LRRC2 | ENSP00000341684 | ENSP00000379241 | Coiled-coil domain containing 15 | Leucine-rich repeat-containing protein 2; Leucine rich repeat containing 2 | 0.766 |
CCDC15 | MYO10 | ENSP00000341684 | ENSP00000421280 | Coiled-coil domain containing 15 | Unconventional myosin-X; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. In hippocampal neurons i [...] | 0.578 |
CCDC15 | OXSM | ENSP00000341684 | ENSP00000280701 | Coiled-coil domain containing 15 | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function; Belongs to the beta-ketoacyl-ACP synthases family | 0.732 |
CCDC15 | SRP68 | ENSP00000341684 | ENSP00000312066 | Coiled-coil domain containing 15 | Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function | 0.617 |
EEF1A1 | C1orf87 | ENSP00000339063 | ENSP00000360244 | Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | 0.800 |
LRRC2 | C1orf87 | ENSP00000379241 | ENSP00000360244 | Leucine-rich repeat-containing protein 2; Leucine rich repeat containing 2 | Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87 | 0.488 |
LRRC2 | CCDC15 | ENSP00000379241 | ENSP00000341684 | Leucine-rich repeat-containing protein 2; Leucine rich repeat containing 2 | Coiled-coil domain containing 15 | 0.766 |