• Version:
  • 11.0 [archived version]
STRINGSTRING
SLC5A7 SLC5A7 SLC23A3 SLC23A3 FAM73A FAM73A LHFPL3 LHFPL3 ZBBX ZBBX SLC44A5 SLC44A5 CLEC10A CLEC10A S100A3 S100A3 C3orf84 C3orf84 TMEM163 TMEM163 PRRC2C PRRC2C
"SLC44A5" - Choline transporter-like protein 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC44A5Choline transporter-like protein 5; Solute carrier family 44 member 5; Belongs to the CTL (choline transporter-like) family (719 aa)    
Predicted Functional Partners:
C3orf84
Uncharacterized protein C3orf84; Chromosome 3 open reading frame 84 (204 aa)
            
  0.730
ZBBX
Zinc finger B-box domain containing (839 aa)
            
  0.657
CLEC10A
C-type lectin domain family 10 member A; Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells; C-type lectin domain containing (316 aa)
      
   
  0.587
FAM73A
Mitoguardin 1; Regulator of mitochondrial fusion- acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family (633 aa)
            
  0.566
SLC23A3
Solute carrier family 23 member 3; Belongs to the xanthine/uracil permease family. Nucleobase-cation symporter-2 (NCS2) (TC 2.A.40) subfamily (618 aa)
      
   
  0.562
LHFPL3
LHFPL tetraspan subfamily member 3 (222 aa)
            
  0.562
TMEM163
Transmembrane protein 163; May bind zinc and other divalent cations and recruit them to vesicular organelles (289 aa)
            
  0.558
SLC5A7
High affinity choline transporter 1; Transmembrane transporter that imports choline from the extracellular space into the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion- and chloride ion-dependent; Belongs to the sodium-solute symporter (SSF) (TC 2.A.21) family (580 aa)
      
   
  0.552
PRRC2C
Protein PRRC2C; Proline rich coiled-coil 2C (2817 aa)
            
  0.548
S100A3
Protein S100-A3; Binds both calcium and zinc. May be involved in calcium- dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation; S100 calcium binding proteins (101 aa)
            
  0.534
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]
STRING is part of the ELIXIR infrastructure: it is one of ELIXIR's Core Data Resources.  Learn more >