CDR1 protein (human) - STRING database

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CDR1

Cerebellar degeneration related protein 1 (262 aa)

Predicted Functional Partners:

CDR2

0.930

FRMD7

0.715

ENSG00000268221

0.711

ENSG00000166160

0.711

PSME3

0.711

SLC25A14

0.710

OPN1LW

0.710

IGHV4-38-2

0.646

NYX

0.641

DUSP5

0.587

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDR1	CDR2	ENSP00000359563	ENSP00000268383	Cerebellar degeneration related protein 1	Cerebellar degeneration related protein 2	0.930
CDR1	DUSP5	ENSP00000359563	ENSP00000358596	Cerebellar degeneration related protein 1	Dual specificity protein phosphatase 5; Dual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. The highest relative activity is toward ERK1; MAP kinase phosphatases	0.587
CDR1	ENSG00000166160	ENSP00000359563	ENSP00000469970	Cerebellar degeneration related protein 1	Opsin 1 (cone pigments), medium-wave-sensitive; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal	0.711
CDR1	ENSG00000268221	ENSP00000359563	ENSP00000472316	Cerebellar degeneration related protein 1	Medium-wave-sensitive opsin 2; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal	0.711
CDR1	FRMD7	ENSP00000359563	ENSP00000298542	Cerebellar degeneration related protein 1	FERM domain-containing protein 7; Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability; FERM domain containing	0.715
CDR1	IGHV4-38-2	ENSP00000359563	ENSP00000478289	Cerebellar degeneration related protein 1	Immunoglobulin heavy variable 4-38-2; V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, whi [...]	0.646
CDR1	NYX	ENSP00000359563	ENSP00000340328	Cerebellar degeneration related protein 1	Nyctalopin	0.641
CDR1	OPN1LW	ENSP00000359563	ENSP00000358967	Cerebellar degeneration related protein 1	Long-wave-sensitive opsin 1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal	0.710
CDR1	PSME3	ENSP00000359563	ENSP00000293362	Cerebellar degeneration related protein 1	Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...]	0.711
CDR1	SLC25A14	ENSP00000359563	ENSP00000477981	Cerebellar degeneration related protein 1	Brain mitochondrial carrier protein 1; Participates in the mitochondrial proton leak measured in brain mitochondria; Belongs to the mitochondrial carrier (TC 2.A.29) family	0.710
CDR2	CDR1	ENSP00000268383	ENSP00000359563	Cerebellar degeneration related protein 2	Cerebellar degeneration related protein 1	0.930
CDR2	DUSP5	ENSP00000268383	ENSP00000358596	Cerebellar degeneration related protein 2	Dual specificity protein phosphatase 5; Dual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. The highest relative activity is toward ERK1; MAP kinase phosphatases	0.669
CDR2	IGHV4-38-2	ENSP00000268383	ENSP00000478289	Cerebellar degeneration related protein 2	Immunoglobulin heavy variable 4-38-2; V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, whi [...]	0.669
DUSP5	CDR1	ENSP00000358596	ENSP00000359563	Dual specificity protein phosphatase 5; Dual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. The highest relative activity is toward ERK1; MAP kinase phosphatases	Cerebellar degeneration related protein 1	0.587
DUSP5	CDR2	ENSP00000358596	ENSP00000268383	Dual specificity protein phosphatase 5; Dual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. The highest relative activity is toward ERK1; MAP kinase phosphatases	Cerebellar degeneration related protein 2	0.669
DUSP5	IGHV4-38-2	ENSP00000358596	ENSP00000478289	Dual specificity protein phosphatase 5; Dual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. The highest relative activity is toward ERK1; MAP kinase phosphatases	Immunoglobulin heavy variable 4-38-2; V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, whi [...]	0.670
ENSG00000166160	CDR1	ENSP00000469970	ENSP00000359563	Opsin 1 (cone pigments), medium-wave-sensitive; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal	Cerebellar degeneration related protein 1	0.711
ENSG00000166160	FRMD7	ENSP00000469970	ENSP00000298542	Opsin 1 (cone pigments), medium-wave-sensitive; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal	FERM domain-containing protein 7; Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability; FERM domain containing	0.710
ENSG00000166160	NYX	ENSP00000469970	ENSP00000340328	Opsin 1 (cone pigments), medium-wave-sensitive; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal	Nyctalopin	0.640
ENSG00000166160	SLC25A14	ENSP00000469970	ENSP00000477981	Opsin 1 (cone pigments), medium-wave-sensitive; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal	Brain mitochondrial carrier protein 1; Participates in the mitochondrial proton leak measured in brain mitochondria; Belongs to the mitochondrial carrier (TC 2.A.29) family	0.641

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