FMR1NB protein (human) - STRING database

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FMR1NB

Fragile X mental retardation 1 neighbor protein; FMR1 neighbor (255 aa)

Predicted Functional Partners:

MORC1

0.741

TAF7

0.696

CRISP2

0.676

NXF2

0.660

NXF2B

0.657

FTHL17

0.642

FATE1

0.633

NXF5

0.626

MKNK1

0.619

INHBC

0.609

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRISP2	FMR1NB	ENSP00000339155	ENSP00000359498	Cysteine-rich secretory protein 2; May regulate some ion channels’ activity and therebye regulate calcium fluxes during sperm capacitation; Cysteine rich secretory protein family	Fragile X mental retardation 1 neighbor protein; FMR1 neighbor	0.676
CRISP2	FTHL17	ENSP00000339155	ENSP00000368207	Cysteine-rich secretory protein 2; May regulate some ion channels’ activity and therebye regulate calcium fluxes during sperm capacitation; Cysteine rich secretory protein family	Ferritin heavy chain like 17	0.631
CRISP2	MORC1	ENSP00000339155	ENSP00000232603	Cysteine-rich secretory protein 2; May regulate some ion channels’ activity and therebye regulate calcium fluxes during sperm capacitation; Cysteine rich secretory protein family	MORC family CW-type zinc finger protein 1; Required for spermatogenesis; Zinc fingers CW-type	0.600
CRISP2	NXF2	ENSP00000339155	ENSP00000485586	Cysteine-rich secretory protein 2; May regulate some ion channels’ activity and therebye regulate calcium fluxes during sperm capacitation; Cysteine rich secretory protein family	Nuclear RNA export factor 2; Involved in the export of mRNA from the nucleus to the cytoplasm; Belongs to the NXF family	0.473
CRISP2	NXF2B	ENSP00000339155	ENSP00000484645	Cysteine-rich secretory protein 2; May regulate some ion channels’ activity and therebye regulate calcium fluxes during sperm capacitation; Cysteine rich secretory protein family	Nuclear RNA export factor 2B; Involved in the export of mRNA from the nucleus to the cytoplasm	0.473
FATE1	FMR1NB	ENSP00000359375	ENSP00000359498	Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling	Fragile X mental retardation 1 neighbor protein; FMR1 neighbor	0.633
FATE1	NXF2	ENSP00000359375	ENSP00000485586	Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling	Nuclear RNA export factor 2; Involved in the export of mRNA from the nucleus to the cytoplasm; Belongs to the NXF family	0.530
FATE1	NXF2B	ENSP00000359375	ENSP00000484645	Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling	Nuclear RNA export factor 2B; Involved in the export of mRNA from the nucleus to the cytoplasm	0.530
FATE1	NXF5	ENSP00000359375	ENSP00000426978	Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling	Nuclear RNA export factor 5; Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons	0.561
FATE1	TAF7	ENSP00000359375	ENSP00000312709	Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling	Transcription initiation factor TFIID subunit 7; Functions as a component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively); Belongs to the TAF7 family	0.569
FMR1NB	CRISP2	ENSP00000359498	ENSP00000339155	Fragile X mental retardation 1 neighbor protein; FMR1 neighbor	Cysteine-rich secretory protein 2; May regulate some ion channels’ activity and therebye regulate calcium fluxes during sperm capacitation; Cysteine rich secretory protein family	0.676
FMR1NB	FATE1	ENSP00000359498	ENSP00000359375	Fragile X mental retardation 1 neighbor protein; FMR1 neighbor	Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling	0.633
FMR1NB	FTHL17	ENSP00000359498	ENSP00000368207	Fragile X mental retardation 1 neighbor protein; FMR1 neighbor	Ferritin heavy chain like 17	0.642
FMR1NB	INHBC	ENSP00000359498	ENSP00000308716	Fragile X mental retardation 1 neighbor protein; FMR1 neighbor	Inhibin beta C chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins; Belongs to the TGF-beta family	0.609
FMR1NB	MKNK1	ENSP00000359498	ENSP00000361014	Fragile X mental retardation 1 neighbor protein; FMR1 neighbor	MAP kinase-interacting serine/threonine-protein kinase 1; May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap; Mitogen-activated protein kinase-activated protein kinases	0.619
FMR1NB	MORC1	ENSP00000359498	ENSP00000232603	Fragile X mental retardation 1 neighbor protein; FMR1 neighbor	MORC family CW-type zinc finger protein 1; Required for spermatogenesis; Zinc fingers CW-type	0.741
FMR1NB	NXF2	ENSP00000359498	ENSP00000485586	Fragile X mental retardation 1 neighbor protein; FMR1 neighbor	Nuclear RNA export factor 2; Involved in the export of mRNA from the nucleus to the cytoplasm; Belongs to the NXF family	0.660
FMR1NB	NXF2B	ENSP00000359498	ENSP00000484645	Fragile X mental retardation 1 neighbor protein; FMR1 neighbor	Nuclear RNA export factor 2B; Involved in the export of mRNA from the nucleus to the cytoplasm	0.657
FMR1NB	NXF5	ENSP00000359498	ENSP00000426978	Fragile X mental retardation 1 neighbor protein; FMR1 neighbor	Nuclear RNA export factor 5; Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons	0.626
FMR1NB	TAF7	ENSP00000359498	ENSP00000312709	Fragile X mental retardation 1 neighbor protein; FMR1 neighbor	Transcription initiation factor TFIID subunit 7; Functions as a component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively); Belongs to the TAF7 family	0.696

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