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STRINGSTRING
POU3F1 POU3F1 PXMP4 PXMP4 RNF17 RNF17 TTL TTL KIAA1107 KIAA1107 CATSPER2 CATSPER2 OSTN OSTN TTLL6 TTLL6 BTBD8 BTBD8 SCRT2 SCRT2
"KIAA1107" - Uncharacterized protein KIAA1107 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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KIAA1107Uncharacterized protein KIAA1107; KIAA1107 (1354 aa)    
Predicted Functional Partners:
TTL
Tubulin--tyrosine ligase; Catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin (377 aa)
      
   
  0.630
BTBD8
BTB/POZ domain-containing protein 8; BTB domain containing 8 (378 aa)
  
            0.612
PXMP4
Peroxisomal membrane protein 4 (212 aa)
            
  0.551
TTLL6
Tubulin polyglutamylase TTLL6; Polyglutamylase which preferentially modifies alpha- tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. Generates long side-chains. Generates polyglutamylation of CGAS/MB21D1, leading to impair the DNA-binding activity of CGAS/MB21D1; Tubulin tyrosine ligase family (891 aa)
      
   
  0.537
CATSPER2
Cation channel sperm-associated protein 2; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte; Belongs to the cation channel sperm-associated (TC 1.A.1.19) family (534 aa)
            
  0.487
OSTN
Osteocrin; Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience. Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex. Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity); Belongs to the Osteocrin family (133 aa)
            
  0.453
SCRT2
Transcriptional repressor scratch 2; May be involved in transcriptional regulation; SNAG transcriptional repressors (307 aa)
      
   
  0.421
POU3F1
POU domain, class 3, transcription factor 1; Transcription factor that binds to the octamer motif (5’-ATTTGCAT-3’). Thought to be involved in early embryogenesis and neurogenesis; POU class homeoboxes and pseudogenes (451 aa)
            
  0.420
RNF17
RING finger protein 17; Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad- MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity); Ring finger proteins (1623 aa)
      
   
  0.416
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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