node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCG4 | SLC17A9 | ENSP00000481728 | ENSP00000359376 | ATP-binding cassette sub-family G member 4; May be involved in macrophage lipid homeostasis; ATP binding cassette subfamily G | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | 0.557 |
ABCG4 | UNC13B | ENSP00000481728 | ENSP00000367756 | ATP-binding cassette sub-family G member 4; May be involved in macrophage lipid homeostasis; ATP binding cassette subfamily G | Protein unc-13 homolog B; Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity); Belongs to the unc-13 family | 0.407 |
GID8 | SLC17A9 | ENSP00000266069 | ENSP00000359376 | Glucose-induced degradation protein 8 homolog; GID complex subunit 8 homolog | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | 0.506 |
MYO5A | SLC17A9 | ENSP00000382177 | ENSP00000359376 | Unconventional myosin-Va; Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation; Myosins, class V | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | 0.508 |
MYO5A | WDTC1 | ENSP00000382177 | ENSP00000317971 | Unconventional myosin-Va; Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation; Myosins, class V | WD and tetratricopeptide repeats protein 1; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors | 0.481 |
PANX1 | SLC17A9 | ENSP00000227638 | ENSP00000359376 | Pannexin-1; Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis; Pannexins | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | 0.555 |
PANX1 | WDTC1 | ENSP00000227638 | ENSP00000317971 | Pannexin-1; Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis; Pannexins | WD and tetratricopeptide repeats protein 1; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors | 0.443 |
PANX3 | SLC17A9 | ENSP00000284288 | ENSP00000359376 | Pannexin-3; Structural component of the gap junctions and the hemichannels; Pannexins | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | 0.518 |
SLC17A9 | ABCG4 | ENSP00000359376 | ENSP00000481728 | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | ATP-binding cassette sub-family G member 4; May be involved in macrophage lipid homeostasis; ATP binding cassette subfamily G | 0.557 |
SLC17A9 | GID8 | ENSP00000359376 | ENSP00000266069 | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | Glucose-induced degradation protein 8 homolog; GID complex subunit 8 homolog | 0.506 |
SLC17A9 | MYO5A | ENSP00000359376 | ENSP00000382177 | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | Unconventional myosin-Va; Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation; Myosins, class V | 0.508 |
SLC17A9 | PANX1 | ENSP00000359376 | ENSP00000227638 | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | Pannexin-1; Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis; Pannexins | 0.555 |
SLC17A9 | PANX3 | ENSP00000359376 | ENSP00000284288 | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | Pannexin-3; Structural component of the gap junctions and the hemichannels; Pannexins | 0.518 |
SLC17A9 | SLC18A3 | ENSP00000359376 | ENSP00000363229 | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | Vesicular acetylcholine transporter; Involved in acetylcholine transport into synaptic vesicles; Solute carriers | 0.524 |
SLC17A9 | SLC37A1 | ENSP00000359376 | ENSP00000344648 | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | Glucose-6-phosphate exchanger SLC37A1; Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6- phosphatase. May not play a role in homeostatic regulation of blood glucose levels; Belongs to the major facilitator superfamily. Organophosphate-Pi antiporter (OPA) (TC 2.A.1.4) family | 0.553 |
SLC17A9 | SLC37A2 | ENSP00000359376 | ENSP00000311833 | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | Glucose-6-phosphate exchanger SLC37A2; Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6- phosphatase. May not play a role in homeostatic regulation of blood glucose levels; Solute carriers | 0.675 |
SLC17A9 | UNC13B | ENSP00000359376 | ENSP00000367756 | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | Protein unc-13 homolog B; Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity); Belongs to the unc-13 family | 0.531 |
SLC17A9 | WDTC1 | ENSP00000359376 | ENSP00000317971 | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | WD and tetratricopeptide repeats protein 1; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors | 0.542 |
SLC18A3 | SLC17A9 | ENSP00000363229 | ENSP00000359376 | Vesicular acetylcholine transporter; Involved in acetylcholine transport into synaptic vesicles; Solute carriers | Solute carrier family 17 member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles; Solute carriers | 0.524 |
SLC18A3 | UNC13B | ENSP00000363229 | ENSP00000367756 | Vesicular acetylcholine transporter; Involved in acetylcholine transport into synaptic vesicles; Solute carriers | Protein unc-13 homolog B; Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity); Belongs to the unc-13 family | 0.947 |