| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FATE1 | FMR1NB | ENSP00000359375 | ENSP00000359498 | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor | 0.633 |
| FATE1 | HSF4 | ENSP00000359375 | ENSP00000264009 | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | Heat shock factor protein 4; DNA-binding protein that specifically binds heat shock promoter elements (HSE). Isoform HSF4A represses transcription while the isoform HSF4B activates transcription | 0.658 |
| FATE1 | NXF2 | ENSP00000359375 | ENSP00000485586 | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | Nuclear RNA export factor 2; Involved in the export of mRNA from the nucleus to the cytoplasm; Belongs to the NXF family | 0.530 |
| FATE1 | NXF5 | ENSP00000359375 | ENSP00000426978 | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | Nuclear RNA export factor 5; Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons | 0.561 |
| FATE1 | RNF183 | ENSP00000359375 | ENSP00000419454 | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | Probable E3 ubiquitin-protein ligase RNF183; May act as a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. May collaborate with FATE1 to restrain BIK protein levels thus regulating apoptotic signaling; Ring finger proteins | 0.626 |
| FATE1 | SPANXC | ENSP00000359375 | ENSP00000351884 | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | Sperm protein associated with the nucleus on the X chromosome C; SPANX family member C; Belongs to the SPAN-X family | 0.585 |
| FATE1 | SPANXD | ENSP00000359375 | ENSP00000359546 | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | Sperm protein associated with the nucleus on the X chromosome D; SPANX family member D; Belongs to the SPAN-X family | 0.634 |
| FATE1 | SYNGR1 | ENSP00000359375 | ENSP00000332287 | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | Synaptogyrin-1; May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity). Involved in the regulation of short-term and long-term synaptic plasticity (By similarity); Belongs to the synaptogyrin family | 0.539 |
| FATE1 | TAF7 | ENSP00000359375 | ENSP00000312709 | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | Transcription initiation factor TFIID subunit 7; Functions as a component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively); Belongs to the TAF7 family | 0.569 |
| FATE1 | TOPAZ1 | ENSP00000359375 | ENSP00000310303 | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | Testis- and ovary-specific PAZ domain-containing protein 1; Testis and ovary specific PAZ domain containing 1 | 0.583 |
| FMR1NB | FATE1 | ENSP00000359498 | ENSP00000359375 | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | 0.633 |
| FMR1NB | NXF2 | ENSP00000359498 | ENSP00000485586 | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor | Nuclear RNA export factor 2; Involved in the export of mRNA from the nucleus to the cytoplasm; Belongs to the NXF family | 0.660 |
| FMR1NB | NXF5 | ENSP00000359498 | ENSP00000426978 | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor | Nuclear RNA export factor 5; Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons | 0.626 |
| FMR1NB | SPANXC | ENSP00000359498 | ENSP00000351884 | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor | Sperm protein associated with the nucleus on the X chromosome C; SPANX family member C; Belongs to the SPAN-X family | 0.448 |
| FMR1NB | SPANXD | ENSP00000359498 | ENSP00000359546 | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor | Sperm protein associated with the nucleus on the X chromosome D; SPANX family member D; Belongs to the SPAN-X family | 0.475 |
| FMR1NB | TAF7 | ENSP00000359498 | ENSP00000312709 | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor | Transcription initiation factor TFIID subunit 7; Functions as a component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively); Belongs to the TAF7 family | 0.696 |
| HSF4 | FATE1 | ENSP00000264009 | ENSP00000359375 | Heat shock factor protein 4; DNA-binding protein that specifically binds heat shock promoter elements (HSE). Isoform HSF4A represses transcription while the isoform HSF4B activates transcription | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | 0.658 |
| NXF2 | FATE1 | ENSP00000485586 | ENSP00000359375 | Nuclear RNA export factor 2; Involved in the export of mRNA from the nucleus to the cytoplasm; Belongs to the NXF family | Fetal and adult testis-expressed transcript protein; Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER- mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling | 0.530 |
| NXF2 | FMR1NB | ENSP00000485586 | ENSP00000359498 | Nuclear RNA export factor 2; Involved in the export of mRNA from the nucleus to the cytoplasm; Belongs to the NXF family | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor | 0.660 |
| NXF2 | SPANXC | ENSP00000485586 | ENSP00000351884 | Nuclear RNA export factor 2; Involved in the export of mRNA from the nucleus to the cytoplasm; Belongs to the NXF family | Sperm protein associated with the nucleus on the X chromosome C; SPANX family member C; Belongs to the SPAN-X family | 0.400 |
