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  • 11.0 [archived version]
STRINGSTRING
CDRT15L2 CDRT15L2 CXorf36 CXorf36 C3orf58 C3orf58 EVI5 EVI5 FAM69A FAM69A RPL5 RPL5 B3GNT8 B3GNT8 ZNF296 ZNF296 TBC1D16 TBC1D16 CEND1 CEND1 VSIG2 VSIG2
"FAM69A" - Protein FAM69A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM69AProtein FAM69A; Family with sequence similarity 69 member A (428 aa)    
Predicted Functional Partners:
CDRT15L2
CMT1A duplicated region transcript 15 like 2 (281 aa)
           
  0.704
VSIG2
V-set and immunoglobulin domain containing 2 (327 aa)
           
  0.570
CXorf36
Deleted in autism-related protein 1; Chromosome X open reading frame 36 (433 aa)
           
  0.569
C3orf58
Deleted in autism protein 1; May play a role in cardiomyocyte proliferation through paracrine signaling and activation of the PPI3K-AKT-CDK7 signaling cascade; Belongs to the DIA1 family (430 aa)
           
  0.558
TBC1D16
TBC1 domain family member 16; May act as a GTPase-activating protein for Rab family protein(s) (767 aa)
           
  0.557
EVI5
Ecotropic viral integration site 5 protein homolog; Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a role in cytokinesis (810 aa)
 
       
  0.546
RPL5
60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (297 aa)
           
  0.542
CEND1
Cell cycle exit and neuronal differentiation protein 1; Involved in neuronal differentiation; Belongs to the CEND1 family (149 aa)
     
   
  0.527
ZNF296
Zinc finger protein 296; May be a transcriptional corepressor with KLF4; Zinc fingers C2H2-type (475 aa)
           
  0.514
B3GNT8
UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase 8; Beta-1,3-N-acetylglucosaminyltransferase that plays a role in the elongation of specific branch structures of multiantennary N-glycans. Has strong activity towards tetraantennary N-glycans and 2,6 triantennary glycans; Belongs to the glycosyltransferase 31 family (397 aa)
           
  0.505
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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