node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C10orf55 | TMEM56 | ENSP00000409225 | ENSP00000359222 | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | Transmembrane protein 56; TLC domain containing | 0.541 |
CCDC144A | TMEM56 | ENSP00000353717 | ENSP00000359222 | Coiled-coil domain containing 144A | Transmembrane protein 56; TLC domain containing | 0.532 |
CCDC74A | CFAP57 | ENSP00000295171 | ENSP00000479773 | Coiled-coil domain containing 74A | Cilia and flagella associated protein 57 | 0.622 |
CCDC74A | SLC25A21 | ENSP00000295171 | ENSP00000329452 | Coiled-coil domain containing 74A | Mitochondrial 2-oxodicarboxylate carrier; Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate; Belongs to the mitochondrial carrier (TC 2.A.29) family | 0.542 |
CCDC74A | TMEM56 | ENSP00000295171 | ENSP00000359222 | Coiled-coil domain containing 74A | Transmembrane protein 56; TLC domain containing | 0.597 |
CFAP57 | CCDC74A | ENSP00000479773 | ENSP00000295171 | Cilia and flagella associated protein 57 | Coiled-coil domain containing 74A | 0.622 |
CFAP57 | SLC25A21 | ENSP00000479773 | ENSP00000329452 | Cilia and flagella associated protein 57 | Mitochondrial 2-oxodicarboxylate carrier; Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate; Belongs to the mitochondrial carrier (TC 2.A.29) family | 0.591 |
CFAP57 | TMEM56 | ENSP00000479773 | ENSP00000359222 | Cilia and flagella associated protein 57 | Transmembrane protein 56; TLC domain containing | 0.554 |
FAM168B | TMEM56 | ENSP00000387051 | ENSP00000359222 | Myelin-associated neurite-outgrowth inhibitor; Modulates neuronal axonal outgrowth by acting as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27 (By similarity) | Transmembrane protein 56; TLC domain containing | 0.621 |
HEPACAM2 | TMEM56 | ENSP00000390204 | ENSP00000359222 | HEPACAM family member 2; Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes- anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation; I-set domain containing | Transmembrane protein 56; TLC domain containing | 0.515 |
METTL8 | TMEM56 | ENSP00000480056 | ENSP00000359222 | Methyltransferase-like protein 8; Probable methyltransferase; Belongs to the methyltransferase superfamily. METL family | Transmembrane protein 56; TLC domain containing | 0.572 |
PLCXD2 | TMEM56 | ENSP00000420686 | ENSP00000359222 | PI-PLC X domain-containing protein 2; Phosphatidylinositol specific phospholipase C X domain containing 2 | Transmembrane protein 56; TLC domain containing | 0.526 |
RWDD3 | TMEM56 | ENSP00000359221 | ENSP00000359222 | RWD domain-containing protein 3; Enhancer of SUMO conjugation. Via its interaction with UBE2I/UBC9, increases SUMO conjugation to proteins by promoting the binding of E1 and E2 enzymes, thioester linkage between SUMO and UBE2I/UBC9 and transfer of SUMO to specific target proteins which include HIF1A, PIAS, NFKBIA, NR3C1 and TOP1. Isoform 1 and isoform 2 positively regulate the NF-kappa-B signaling pathway by enhancing the sumoylation of NF-kappa-B inhibitor alpha (NFKBIA), promoting its stabilization which consequently leads to an increased inhibition of NF-kappa-B transcriptional acti [...] | Transmembrane protein 56; TLC domain containing | 0.598 |
SLC25A21 | CCDC74A | ENSP00000329452 | ENSP00000295171 | Mitochondrial 2-oxodicarboxylate carrier; Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate; Belongs to the mitochondrial carrier (TC 2.A.29) family | Coiled-coil domain containing 74A | 0.542 |
SLC25A21 | CFAP57 | ENSP00000329452 | ENSP00000479773 | Mitochondrial 2-oxodicarboxylate carrier; Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate; Belongs to the mitochondrial carrier (TC 2.A.29) family | Cilia and flagella associated protein 57 | 0.591 |
SLC25A21 | TMEM56 | ENSP00000329452 | ENSP00000359222 | Mitochondrial 2-oxodicarboxylate carrier; Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate; Belongs to the mitochondrial carrier (TC 2.A.29) family | Transmembrane protein 56; TLC domain containing | 0.496 |
TMEM56 | C10orf55 | ENSP00000359222 | ENSP00000409225 | Transmembrane protein 56; TLC domain containing | Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55 | 0.541 |
TMEM56 | CCDC144A | ENSP00000359222 | ENSP00000353717 | Transmembrane protein 56; TLC domain containing | Coiled-coil domain containing 144A | 0.532 |
TMEM56 | CCDC74A | ENSP00000359222 | ENSP00000295171 | Transmembrane protein 56; TLC domain containing | Coiled-coil domain containing 74A | 0.597 |
TMEM56 | CFAP57 | ENSP00000359222 | ENSP00000479773 | Transmembrane protein 56; TLC domain containing | Cilia and flagella associated protein 57 | 0.554 |