DPCD protein (human) - STRING database

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DPCD

Protein DPCD; May play a role in the formation or function of ciliated cells (203 aa)

Predicted Functional Partners:

RUVBL1

0.909

RUVBL2

0.854

FBXW4

0.798

POLL

0.791

DNAL4

0.725

DNAL1

0.724

DNALI1

0.719

LBX1

0.711

CFAP221

0.701

WDR11

0.650

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFAP221	DNAL1	ENSP00000393222	ENSP00000452037	Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated	Dynein light chain 1, axonemal; Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-rig [...]	0.421
CFAP221	DNALI1	ENSP00000393222	ENSP00000296218	Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated	Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family	0.414
CFAP221	DPCD	ENSP00000393222	ENSP00000359170	Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated	Protein DPCD; May play a role in the formation or function of ciliated cells	0.701
DNAL1	CFAP221	ENSP00000452037	ENSP00000393222	Dynein light chain 1, axonemal; Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-rig [...]	Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated	0.421
DNAL1	DNAL4	ENSP00000452037	ENSP00000216068	Dynein light chain 1, axonemal; Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-rig [...]	Dynein light chain 4, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity); Dyneins, axonemal	0.876
DNAL1	DNALI1	ENSP00000452037	ENSP00000296218	Dynein light chain 1, axonemal; Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-rig [...]	Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family	0.895
DNAL1	DPCD	ENSP00000452037	ENSP00000359170	Dynein light chain 1, axonemal; Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-rig [...]	Protein DPCD; May play a role in the formation or function of ciliated cells	0.724
DNAL4	DNAL1	ENSP00000216068	ENSP00000452037	Dynein light chain 4, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity); Dyneins, axonemal	Dynein light chain 1, axonemal; Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-rig [...]	0.876
DNAL4	DNALI1	ENSP00000216068	ENSP00000296218	Dynein light chain 4, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity); Dyneins, axonemal	Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family	0.881
DNAL4	DPCD	ENSP00000216068	ENSP00000359170	Dynein light chain 4, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity); Dyneins, axonemal	Protein DPCD; May play a role in the formation or function of ciliated cells	0.725
DNALI1	CFAP221	ENSP00000296218	ENSP00000393222	Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family	Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated	0.414
DNALI1	DNAL1	ENSP00000296218	ENSP00000452037	Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family	Dynein light chain 1, axonemal; Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-rig [...]	0.895
DNALI1	DNAL4	ENSP00000296218	ENSP00000216068	Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family	Dynein light chain 4, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity); Dyneins, axonemal	0.881
DNALI1	DPCD	ENSP00000296218	ENSP00000359170	Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family	Protein DPCD; May play a role in the formation or function of ciliated cells	0.719
DPCD	CFAP221	ENSP00000359170	ENSP00000393222	Protein DPCD; May play a role in the formation or function of ciliated cells	Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated	0.701
DPCD	DNAL1	ENSP00000359170	ENSP00000452037	Protein DPCD; May play a role in the formation or function of ciliated cells	Dynein light chain 1, axonemal; Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-rig [...]	0.724
DPCD	DNAL4	ENSP00000359170	ENSP00000216068	Protein DPCD; May play a role in the formation or function of ciliated cells	Dynein light chain 4, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity); Dyneins, axonemal	0.725
DPCD	DNALI1	ENSP00000359170	ENSP00000296218	Protein DPCD; May play a role in the formation or function of ciliated cells	Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family	0.719
DPCD	FBXW4	ENSP00000359170	ENSP00000359149	Protein DPCD; May play a role in the formation or function of ciliated cells	F-box/WD repeat-containing protein 4; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling; F-box and WD repeat domain containing	0.798
DPCD	LBX1	ENSP00000359170	ENSP00000359212	Protein DPCD; May play a role in the formation or function of ciliated cells	Transcription factor LBX1; Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord; NKL subclass homeoboxes and pseudogenes	0.711

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