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  • 11.0 [archived version]
STRINGSTRING
RNF214 RNF214 TVP23C TVP23C SAYSD1 SAYSD1 TRMT13 TRMT13 CHAMP1 CHAMP1 ZNF532 ZNF532 TPGS2 TPGS2 NXT2 NXT2 PIGH PIGH LRRC8B LRRC8B C5orf22 C5orf22
"TRMT13" - tRNA:m(4)X modification enzyme TRM13 homolog in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
TRMT13tRNA-m(4)X modification enzyme TRM13 homolog; tRNA methylase which 2’-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His) (481 aa)    
Predicted Functional Partners:
SAYSD1
SAYSVFN motif domain containing 1 (183 aa)
            
  0.767
C5orf22
UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family (442 aa)
      
   
  0.753
TPGS2
Tubulin polyglutamylase complex subunit 2 (304 aa)
            
  0.749
PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis (188 aa)
            
  0.667
CHAMP1
Chromosome alignment-maintaining phosphoprotein 1; Required for proper alignment of chromosomes at metaphase and their accurate segregation during mitosis. Involved in the maintenance of spindle microtubules attachment to the kinetochore during sister chromatid biorientation. May recruit CENPE and CENPF to the kinetochore; Zinc fingers C2H2-type (812 aa)
            
  0.667
LRRC8B
Volume-regulated anion channel subunit LRRC8B; Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition (803 aa)
            
  0.660
NXT2
NTF2-related export protein 2; Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export (197 aa)
            
  0.655
TVP23C
Trans-golgi network vesicle protein 23 homolog C; Belongs to the TVP23 family (276 aa)
            
  0.644
RNF214
Ring finger protein 214 (703 aa)
            
  0.641
ZNF532
Zinc finger protein 532; May be involved in transcriptional regulation; Zinc fingers C2H2-type (1301 aa)
            
  0.628
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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