AMY1A protein (human) - STRING database

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Score

AMY1A

Amylase, alpha 1A (511 aa)

Predicted Functional Partners:

LOC93432

0.984

MGAM

0.970

SI

0.964

AMY1B

0.952

GBE1

0.931

GANC

0.920

GAA

0.874

PYGB

0.841

PYGL

0.821

PYGM

0.821

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMY1A	AMY1B	ENSP00000359100	ENSP00000330484	Amylase, alpha 1A	Amylase, alpha 1B	0.952
AMY1A	GAA	ENSP00000359100	ENSP00000305692	Amylase, alpha 1A	Lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans	0.874
AMY1A	GANC	ENSP00000359100	ENSP00000326227	Amylase, alpha 1A	Neutral alpha-glucosidase C; Has alpha-glucosidase activity	0.920
AMY1A	GBE1	ENSP00000359100	ENSP00000410833	Amylase, alpha 1A	1,4-alpha-glucan-branching enzyme; Required for normal glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule (Probable); Belongs to the glycosyl hydrolase 13 family. GlgB subfamily	0.931
AMY1A	LOC93432	ENSP00000359100	ENSP00000447431	Amylase, alpha 1A	Probable maltase-glucoamylase 2; Homo sapiens maltase-glucoamylase (alpha-glucosidase) (LOC93432), mRNA	0.984
AMY1A	MGAM	ENSP00000359100	ENSP00000447378	Amylase, alpha 1A	Maltase-glucoamylase, intestinal; May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing	0.970
AMY1A	PYGB	ENSP00000359100	ENSP00000216962	Amylase, alpha 1A	Glycogen phosphorylase, brain form; Glycogen phosphorylase that regulates glycogen mobilization. Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	0.841
AMY1A	PYGL	ENSP00000359100	ENSP00000216392	Amylase, alpha 1A	Glycogen phosphorylase, liver form; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	0.821
AMY1A	PYGM	ENSP00000359100	ENSP00000164139	Amylase, alpha 1A	Glycogen phosphorylase, muscle form; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	0.821
AMY1A	SI	ENSP00000359100	ENSP00000264382	Amylase, alpha 1A	Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family	0.964
AMY1B	AMY1A	ENSP00000330484	ENSP00000359100	Amylase, alpha 1B	Amylase, alpha 1A	0.952
AMY1B	MGAM	ENSP00000330484	ENSP00000447378	Amylase, alpha 1B	Maltase-glucoamylase, intestinal; May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing	0.485
AMY1B	PYGB	ENSP00000330484	ENSP00000216962	Amylase, alpha 1B	Glycogen phosphorylase, brain form; Glycogen phosphorylase that regulates glycogen mobilization. Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	0.422
AMY1B	SI	ENSP00000330484	ENSP00000264382	Amylase, alpha 1B	Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family	0.563
GAA	AMY1A	ENSP00000305692	ENSP00000359100	Lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans	Amylase, alpha 1A	0.874
GAA	GBE1	ENSP00000305692	ENSP00000410833	Lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans	1,4-alpha-glucan-branching enzyme; Required for normal glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule (Probable); Belongs to the glycosyl hydrolase 13 family. GlgB subfamily	0.608
GAA	LOC93432	ENSP00000305692	ENSP00000447431	Lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans	Probable maltase-glucoamylase 2; Homo sapiens maltase-glucoamylase (alpha-glucosidase) (LOC93432), mRNA	0.906
GAA	MGAM	ENSP00000305692	ENSP00000447378	Lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans	Maltase-glucoamylase, intestinal; May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing	0.907
GAA	PYGM	ENSP00000305692	ENSP00000164139	Lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans	Glycogen phosphorylase, muscle form; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	0.558
GAA	SI	ENSP00000305692	ENSP00000264382	Lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans	Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides; Belongs to the glycosyl hydrolase 31 family	0.908

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