node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFTPH | C10orf76 | ENSP00000238855 | ENSP00000359050 | Aftiphilin; May play a role in membrane trafficking | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | 0.719 |
AFTPH | CCNL1 | ENSP00000238855 | ENSP00000295926 | Aftiphilin; May play a role in membrane trafficking | Cyclin-L1; Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs). Inhibited by the CDK-specific inhibitor CDKN1A/p21. May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC) | 0.555 |
AFTPH | FAM84B | ENSP00000238855 | ENSP00000302578 | Aftiphilin; May play a role in membrane trafficking | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | 0.517 |
AFTPH | KCNRG | ENSP00000238855 | ENSP00000324191 | Aftiphilin; May play a role in membrane trafficking | Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes | 0.540 |
AMMECR1L | C10orf76 | ENSP00000272647 | ENSP00000359050 | AMMECR1-like protein; AMMECR1 like | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | 0.530 |
AMMECR1L | CC2D1B | ENSP00000272647 | ENSP00000360642 | AMMECR1-like protein; AMMECR1 like | Coiled-coil and C2 domain-containing protein 1B; Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells; C2 domain containing | 0.601 |
AMMECR1L | GPATCH3 | ENSP00000272647 | ENSP00000354645 | AMMECR1-like protein; AMMECR1 like | G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6; G [...] | 0.599 |
ATP6V1C1 | C10orf76 | ENSP00000379203 | ENSP00000359050 | V-type proton ATPase subunit C 1; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | 0.626 |
ATP6V1C1 | SEPT3 | ENSP00000379203 | ENSP00000379704 | V-type proton ATPase subunit C 1; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | Neuronal-specific septin-3; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Septin GTPase family | 0.570 |
C10orf76 | AFTPH | ENSP00000359050 | ENSP00000238855 | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | Aftiphilin; May play a role in membrane trafficking | 0.719 |
C10orf76 | AMMECR1L | ENSP00000359050 | ENSP00000272647 | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | AMMECR1-like protein; AMMECR1 like | 0.530 |
C10orf76 | ATP6V1C1 | ENSP00000359050 | ENSP00000379203 | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | V-type proton ATPase subunit C 1; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | 0.626 |
C10orf76 | CC2D1B | ENSP00000359050 | ENSP00000360642 | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | Coiled-coil and C2 domain-containing protein 1B; Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells; C2 domain containing | 0.547 |
C10orf76 | CCNL1 | ENSP00000359050 | ENSP00000295926 | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | Cyclin-L1; Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs). Inhibited by the CDK-specific inhibitor CDKN1A/p21. May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC) | 0.559 |
C10orf76 | FAM84B | ENSP00000359050 | ENSP00000302578 | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | 0.577 |
C10orf76 | GPATCH3 | ENSP00000359050 | ENSP00000354645 | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6; G [...] | 0.554 |
C10orf76 | KCNRG | ENSP00000359050 | ENSP00000324191 | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes | 0.573 |
C10orf76 | SEPT3 | ENSP00000359050 | ENSP00000379704 | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | Neuronal-specific septin-3; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. Septin GTPase family | 0.626 |
C10orf76 | ZNF547 | ENSP00000359050 | ENSP00000282282 | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | Zinc finger protein 547; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.709 |
CC2D1B | AMMECR1L | ENSP00000360642 | ENSP00000272647 | Coiled-coil and C2 domain-containing protein 1B; Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells; C2 domain containing | AMMECR1-like protein; AMMECR1 like | 0.601 |