| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LUC7L | LUC7L3 | ENSP00000293872 | ENSP00000425092 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain; Belongs to the Luc7 family | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing; Belongs to the Luc7 family | 0.831 |
| LUC7L | PNN | ENSP00000293872 | ENSP00000216832 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain; Belongs to the Luc7 family | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5’CAGGTG-3’. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulatio [...] | 0.413 |
| LUC7L | PRPF38A | ENSP00000293872 | ENSP00000257181 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain; Belongs to the Luc7 family | Pre-mRNA-splicing factor 38A; May be required for pre-mRNA splicing; Belongs to the PRP38 family | 0.499 |
| LUC7L | PRPF38B | ENSP00000293872 | ENSP00000359042 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain; Belongs to the Luc7 family | Pre-mRNA-splicing factor 38B; May be required for pre-mRNA splicing | 0.769 |
| LUC7L | RBM25 | ENSP00000293872 | ENSP00000261973 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain; Belongs to the Luc7 family | RNA-binding protein 25; RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5’-splice site (5’-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5’-ss usage through the 5’-CGGGCA-3’ RNA sequence. Its association with LUC7 [...] | 0.955 |
| LUC7L | RBM39 | ENSP00000293872 | ENSP00000253363 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain; Belongs to the Luc7 family | RNA-binding protein 39; Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process; RNA binding motif containing | 0.830 |
| LUC7L | SNRPB2 | ENSP00000293872 | ENSP00000246071 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain; Belongs to the Luc7 family | U2 small nuclear ribonucleoprotein B’; Involved in pre-mRNA splicing. This protein is associated with snRNP U2. It binds stem loop IV of U2 snRNA only in presence of the U2A’ protein; RNA binding motif containing | 0.616 |
| LUC7L | SRSF11 | ENSP00000293872 | ENSP00000359988 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain; Belongs to the Luc7 family | Serine/arginine-rich splicing factor 11; May function in pre-mRNA splicing; RNA binding motif containing | 0.746 |
| LUC7L3 | LUC7L | ENSP00000425092 | ENSP00000293872 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing; Belongs to the Luc7 family | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain; Belongs to the Luc7 family | 0.831 |
| LUC7L3 | PNN | ENSP00000425092 | ENSP00000216832 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing; Belongs to the Luc7 family | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5’CAGGTG-3’. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulatio [...] | 0.925 |
| LUC7L3 | PRPF38B | ENSP00000425092 | ENSP00000359042 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing; Belongs to the Luc7 family | Pre-mRNA-splicing factor 38B; May be required for pre-mRNA splicing | 0.710 |
| LUC7L3 | RBM25 | ENSP00000425092 | ENSP00000261973 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing; Belongs to the Luc7 family | RNA-binding protein 25; RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5’-splice site (5’-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5’-ss usage through the 5’-CGGGCA-3’ RNA sequence. Its association with LUC7 [...] | 0.975 |
| LUC7L3 | RBM39 | ENSP00000425092 | ENSP00000253363 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing; Belongs to the Luc7 family | RNA-binding protein 39; Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process; RNA binding motif containing | 0.573 |
| LUC7L3 | RCC1 | ENSP00000425092 | ENSP00000362937 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing; Belongs to the Luc7 family | Regulator of chromosome condensation; Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly | 0.490 |
| LUC7L3 | SNRPB2 | ENSP00000425092 | ENSP00000246071 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing; Belongs to the Luc7 family | U2 small nuclear ribonucleoprotein B’; Involved in pre-mRNA splicing. This protein is associated with snRNP U2. It binds stem loop IV of U2 snRNA only in presence of the U2A’ protein; RNA binding motif containing | 0.633 |
| LUC7L3 | SRSF11 | ENSP00000425092 | ENSP00000359988 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing; Belongs to the Luc7 family | Serine/arginine-rich splicing factor 11; May function in pre-mRNA splicing; RNA binding motif containing | 0.869 |
| PNN | LUC7L | ENSP00000216832 | ENSP00000293872 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5’CAGGTG-3’. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulatio [...] | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain; Belongs to the Luc7 family | 0.413 |
| PNN | LUC7L3 | ENSP00000216832 | ENSP00000425092 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5’CAGGTG-3’. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulatio [...] | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing; Belongs to the Luc7 family | 0.925 |
| PNN | PRPF38B | ENSP00000216832 | ENSP00000359042 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5’CAGGTG-3’. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulatio [...] | Pre-mRNA-splicing factor 38B; May be required for pre-mRNA splicing | 0.868 |
| PNN | RBM25 | ENSP00000216832 | ENSP00000261973 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5’CAGGTG-3’. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulatio [...] | RNA-binding protein 25; RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5’-splice site (5’-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5’-ss usage through the 5’-CGGGCA-3’ RNA sequence. Its association with LUC7 [...] | 0.920 |
