STRIP1 protein (human) - STRING database

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STRIP1

Striatin-interacting protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape; STRIPAK complex (837 aa)

Predicted Functional Partners:

SLMAP

0.979

STRN

0.976

STRN4

0.973

MOB4

0.970

FGFR1OP2

0.963

STRN3

0.963

MST4

0.961

CTTNBP2NL

0.960

SIKE1

0.959

STK25

0.949

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTTNBP2NL	FGFR1OP2	ENSP00000271277	ENSP00000229395	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	0.668
CTTNBP2NL	MOB4	ENSP00000271277	ENSP00000315702	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	0.952
CTTNBP2NL	MST4	ENSP00000271277	ENSP00000377867	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Serine/threonine-protein kinase 26; Mediator of cell growth. Modulates apoptosis. In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily	0.929
CTTNBP2NL	SIKE1	ENSP00000271277	ENSP00000358541	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Suppressor of IKBKE 1; Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways; Belongs to the SIKE family	0.570
CTTNBP2NL	SLMAP	ENSP00000271277	ENSP00000295951	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Sarcolemmal membrane-associated protein; May play a role during myoblast fusion; STRIPAK complex	0.718
CTTNBP2NL	STK25	ENSP00000271277	ENSP00000325748	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Serine/threonine-protein kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration	0.904
CTTNBP2NL	STRIP1	ENSP00000271277	ENSP00000358810	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Striatin-interacting protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape; STRIPAK complex	0.960
CTTNBP2NL	STRN	ENSP00000271277	ENSP00000263918	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Striatin; Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling; Belongs to the WD repeat striatin family	0.954
CTTNBP2NL	STRN3	ENSP00000271277	ENSP00000350071	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Protein phosphatase 2 regulatory subunits	0.942
CTTNBP2NL	STRN4	ENSP00000271277	ENSP00000375777	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family	0.963
FGFR1OP2	CTTNBP2NL	ENSP00000229395	ENSP00000271277	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like; STRIPAK complex	0.668
FGFR1OP2	MOB4	ENSP00000229395	ENSP00000315702	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	0.939
FGFR1OP2	MST4	ENSP00000229395	ENSP00000377867	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Serine/threonine-protein kinase 26; Mediator of cell growth. Modulates apoptosis. In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily	0.918
FGFR1OP2	SIKE1	ENSP00000229395	ENSP00000358541	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Suppressor of IKBKE 1; Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways; Belongs to the SIKE family	0.866
FGFR1OP2	SLMAP	ENSP00000229395	ENSP00000295951	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Sarcolemmal membrane-associated protein; May play a role during myoblast fusion; STRIPAK complex	0.883
FGFR1OP2	STK25	ENSP00000229395	ENSP00000325748	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Serine/threonine-protein kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration	0.908
FGFR1OP2	STRIP1	ENSP00000229395	ENSP00000358810	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Striatin-interacting protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape; STRIPAK complex	0.963
FGFR1OP2	STRN	ENSP00000229395	ENSP00000263918	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Striatin; Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling; Belongs to the WD repeat striatin family	0.937
FGFR1OP2	STRN3	ENSP00000229395	ENSP00000350071	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Protein phosphatase 2 regulatory subunits	0.916
FGFR1OP2	STRN4	ENSP00000229395	ENSP00000375777	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family	0.791

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