MAB21L3 protein (human) - STRING database

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MAB21L3

Protein mab-21-like 3; Mab-21 like 3 (362 aa)

Predicted Functional Partners:

ANKRD36B

0.740

MB21D2

0.718

FAM46D

0.691

TAMM41

0.673

FAM184B

0.663

GMNC

0.628

TMEM109

0.604

MIEF1

0.591

PSMG1

0.589

PAPOLG

0.584

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD36B	MAB21L3	ENSP00000481149	ENSP00000358512	Ankyrin repeat domain-containing protein 36B; Ankyrin repeat domain containing; Belongs to the ANKRD36 family	Protein mab-21-like 3; Mab-21 like 3	0.740
FAM184B	MAB21L3	ENSP00000265018	ENSP00000358512	Protein FAM184B; Family with sequence similarity 184 member B; Belongs to the FAM184 family	Protein mab-21-like 3; Mab-21 like 3	0.663
FAM184B	MB21D2	ENSP00000265018	ENSP00000376246	Protein FAM184B; Family with sequence similarity 184 member B; Belongs to the FAM184 family	Protein MB21D2; Mab-21 domain containing 2	0.519
FAM184B	PSMG1	ENSP00000265018	ENSP00000329915	Protein FAM184B; Family with sequence similarity 184 member B; Belongs to the FAM184 family	Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization	0.542
FAM184B	TMEM109	ENSP00000265018	ENSP00000227525	Protein FAM184B; Family with sequence similarity 184 member B; Belongs to the FAM184 family	Transmembrane protein 109; May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death. Can form voltage-gated calcium and potassium channels in vitro (By similarity)	0.568
FAM46D	MAB21L3	ENSP00000443410	ENSP00000358512	Putative nucleotidyltransferase FAM46D; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase	Protein mab-21-like 3; Mab-21 like 3	0.691
FAM46D	MB21D2	ENSP00000443410	ENSP00000376246	Putative nucleotidyltransferase FAM46D; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase	Protein MB21D2; Mab-21 domain containing 2	0.729
FAM46D	MIEF1	ENSP00000443410	ENSP00000327124	Putative nucleotidyltransferase FAM46D; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase	Mitochondrial dynamics protein MID51; Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assem [...]	0.631
FAM46D	PAPOLG	ENSP00000443410	ENSP00000238714	Putative nucleotidyltransferase FAM46D; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase	Poly(A) polymerase gamma; Responsible for the post-transcriptional adenylation of the 3’-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA	0.650
FAM46D	TAMM41	ENSP00000443410	ENSP00000398596	Putative nucleotidyltransferase FAM46D; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase	Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane (By similarity); Belongs to the TAM41 family	0.678
GMNC	MAB21L3	ENSP00000406164	ENSP00000358512	Geminin coiled-coil domain-containing protein 1; Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2- dependent recruitment of CDC45L onto replication origins (By similarity)	Protein mab-21-like 3; Mab-21 like 3	0.628
MAB21L3	ANKRD36B	ENSP00000358512	ENSP00000481149	Protein mab-21-like 3; Mab-21 like 3	Ankyrin repeat domain-containing protein 36B; Ankyrin repeat domain containing; Belongs to the ANKRD36 family	0.740
MAB21L3	FAM184B	ENSP00000358512	ENSP00000265018	Protein mab-21-like 3; Mab-21 like 3	Protein FAM184B; Family with sequence similarity 184 member B; Belongs to the FAM184 family	0.663
MAB21L3	FAM46D	ENSP00000358512	ENSP00000443410	Protein mab-21-like 3; Mab-21 like 3	Putative nucleotidyltransferase FAM46D; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase	0.691
MAB21L3	GMNC	ENSP00000358512	ENSP00000406164	Protein mab-21-like 3; Mab-21 like 3	Geminin coiled-coil domain-containing protein 1; Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2- dependent recruitment of CDC45L onto replication origins (By similarity)	0.628
MAB21L3	MB21D2	ENSP00000358512	ENSP00000376246	Protein mab-21-like 3; Mab-21 like 3	Protein MB21D2; Mab-21 domain containing 2	0.718
MAB21L3	MIEF1	ENSP00000358512	ENSP00000327124	Protein mab-21-like 3; Mab-21 like 3	Mitochondrial dynamics protein MID51; Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assem [...]	0.591
MAB21L3	PAPOLG	ENSP00000358512	ENSP00000238714	Protein mab-21-like 3; Mab-21 like 3	Poly(A) polymerase gamma; Responsible for the post-transcriptional adenylation of the 3’-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA	0.584
MAB21L3	PSMG1	ENSP00000358512	ENSP00000329915	Protein mab-21-like 3; Mab-21 like 3	Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization	0.589
MAB21L3	TAMM41	ENSP00000358512	ENSP00000398596	Protein mab-21-like 3; Mab-21 like 3	Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane (By similarity); Belongs to the TAM41 family	0.673

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