node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD20A1 | CBWD7 | ENSP00000477695 | ENSP00000366608 | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1 | COBW domain-containing protein 6; COBW domain containing 7; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily | 0.684 |
ANKRD20A1 | FAM72B | ENSP00000477695 | ENSP00000358397 | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1 | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family | 0.588 |
ANKRD20A2 | ARHGAP11B | ENSP00000366826 | ENSP00000481934 | Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity; Rho GTPase activating proteins | 0.525 |
ANKRD20A2 | CBWD7 | ENSP00000366826 | ENSP00000366608 | Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2 | COBW domain-containing protein 6; COBW domain containing 7; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily | 0.706 |
ANKRD20A2 | FAM72B | ENSP00000366826 | ENSP00000358397 | Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2 | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family | 0.629 |
ANKRD20A4 | ARHGAP11B | ENSP00000349891 | ENSP00000481934 | Ankyrin repeat domain-containing protein 20A4; Ankyrin repeat domain 20 family member A4 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity; Rho GTPase activating proteins | 0.525 |
ANKRD20A4 | CBWD7 | ENSP00000349891 | ENSP00000366608 | Ankyrin repeat domain-containing protein 20A4; Ankyrin repeat domain 20 family member A4 | COBW domain-containing protein 6; COBW domain containing 7; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily | 0.706 |
ANKRD20A4 | FAM72B | ENSP00000349891 | ENSP00000358397 | Ankyrin repeat domain-containing protein 20A4; Ankyrin repeat domain 20 family member A4 | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family | 0.629 |
ARHGAP11A | FAM72B | ENSP00000355090 | ENSP00000358397 | Rho GTPase activating protein 11A | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family | 0.586 |
ARHGAP11A | TTK | ENSP00000355090 | ENSP00000358813 | Rho GTPase activating protein 11A | Dual specificity protein kinase TTK; Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint | 0.903 |
ARHGAP11B | ANKRD20A2 | ENSP00000481934 | ENSP00000366826 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity; Rho GTPase activating proteins | Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2 | 0.525 |
ARHGAP11B | ANKRD20A4 | ENSP00000481934 | ENSP00000349891 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity; Rho GTPase activating proteins | Ankyrin repeat domain-containing protein 20A4; Ankyrin repeat domain 20 family member A4 | 0.525 |
ARHGAP11B | CBWD7 | ENSP00000481934 | ENSP00000366608 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity; Rho GTPase activating proteins | COBW domain-containing protein 6; COBW domain containing 7; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily | 0.535 |
ARHGAP11B | FAM72B | ENSP00000481934 | ENSP00000358397 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity; Rho GTPase activating proteins | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family | 0.587 |
ARHGAP11B | TTK | ENSP00000481934 | ENSP00000358813 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity; Rho GTPase activating proteins | Dual specificity protein kinase TTK; Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint | 0.737 |
CBWD7 | ANKRD20A1 | ENSP00000366608 | ENSP00000477695 | COBW domain-containing protein 6; COBW domain containing 7; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily | Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1 | 0.684 |
CBWD7 | ANKRD20A2 | ENSP00000366608 | ENSP00000366826 | COBW domain-containing protein 6; COBW domain containing 7; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily | Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2 | 0.706 |
CBWD7 | ANKRD20A4 | ENSP00000366608 | ENSP00000349891 | COBW domain-containing protein 6; COBW domain containing 7; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily | Ankyrin repeat domain-containing protein 20A4; Ankyrin repeat domain 20 family member A4 | 0.706 |
CBWD7 | ARHGAP11B | ENSP00000366608 | ENSP00000481934 | COBW domain-containing protein 6; COBW domain containing 7; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity; Rho GTPase activating proteins | 0.535 |
CBWD7 | FAM72B | ENSP00000366608 | ENSP00000358397 | COBW domain-containing protein 6; COBW domain containing 7; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family | 0.623 |