SCML4 protein (human) - STRING database

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SCML4

Sex comb on midleg-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity); Sterile alpha motif domain containing (414 aa)

Predicted Functional Partners:

ZNF367

0.736

LRRC61

0.619

ACTR3C

0.531

ODF3B

0.519

PIWIL3

0.510

ZNF831

0.508

ZNF560

0.496

TMED3

0.475

IFFO1

0.473

C1orf109

0.473

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTR3C	C1orf109	ENSP00000252071	ENSP00000350704	Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	0.426
ACTR3C	LRRC61	ENSP00000252071	ENSP00000352642	Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins	Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61	0.702
ACTR3C	SCML4	ENSP00000252071	ENSP00000358016	Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins	Sex comb on midleg-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity); Sterile alpha motif domain containing	0.531
C1orf109	ACTR3C	ENSP00000350704	ENSP00000252071	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins	0.426
C1orf109	IFFO1	ENSP00000350704	ENSP00000482285	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	Intermediate filament family orphan 1; Belongs to the intermediate filament family	0.475
C1orf109	LRRC61	ENSP00000350704	ENSP00000352642	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61	0.523
C1orf109	SCML4	ENSP00000350704	ENSP00000358016	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	Sex comb on midleg-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity); Sterile alpha motif domain containing	0.473
IFFO1	C1orf109	ENSP00000482285	ENSP00000350704	Intermediate filament family orphan 1; Belongs to the intermediate filament family	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	0.475
IFFO1	LRRC61	ENSP00000482285	ENSP00000352642	Intermediate filament family orphan 1; Belongs to the intermediate filament family	Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61	0.473
IFFO1	SCML4	ENSP00000482285	ENSP00000358016	Intermediate filament family orphan 1; Belongs to the intermediate filament family	Sex comb on midleg-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity); Sterile alpha motif domain containing	0.473
LRRC61	ACTR3C	ENSP00000352642	ENSP00000252071	Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61	Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins	0.702
LRRC61	C1orf109	ENSP00000352642	ENSP00000350704	Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	0.523
LRRC61	IFFO1	ENSP00000352642	ENSP00000482285	Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61	Intermediate filament family orphan 1; Belongs to the intermediate filament family	0.473
LRRC61	SCML4	ENSP00000352642	ENSP00000358016	Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61	Sex comb on midleg-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity); Sterile alpha motif domain containing	0.619
ODF3B	SCML4	ENSP00000382804	ENSP00000358016	Outer dense fiber of sperm tails 3B	Sex comb on midleg-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity); Sterile alpha motif domain containing	0.519
ODF3B	TMED3	ENSP00000382804	ENSP00000299705	Outer dense fiber of sperm tails 3B	Transmembrane emp24 domain-containing protein 3; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network; Belongs to the EMP24/GP25L family	0.474
PIWIL3	SCML4	ENSP00000330031	ENSP00000358016	Piwi-like protein 3; May play a role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequen [...]	Sex comb on midleg-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity); Sterile alpha motif domain containing	0.510
SCML4	ACTR3C	ENSP00000358016	ENSP00000252071	Sex comb on midleg-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity); Sterile alpha motif domain containing	Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells; Actin related proteins	0.531
SCML4	C1orf109	ENSP00000358016	ENSP00000350704	Sex comb on midleg-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity); Sterile alpha motif domain containing	Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition	0.473
SCML4	IFFO1	ENSP00000358016	ENSP00000482285	Sex comb on midleg-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity); Sterile alpha motif domain containing	Intermediate filament family orphan 1; Belongs to the intermediate filament family	0.473

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