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STRINGSTRING
KPRP KPRP LCE3E LCE3E S100A3 S100A3 LELP1 LELP1 SPRR4 SPRR4 S100A2 S100A2 TCHHL1 TCHHL1 LINGO4 LINGO4 S100A7L2 S100A7L2 S100A7 S100A7 S100A4 S100A4
"TCHHL1" - S100 fused type protein family in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCHHL1S100 fused type protein family; Belongs to the S-100 family (904 aa)    
Predicted Functional Partners:
S100A7L2
S100 calcium binding protein A7 like 2; EF-hand domain containing (112 aa)
      
   
  0.778
S100A2
Protein S100-A2; May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth; EF-hand domain containing (97 aa)
            
  0.766
SPRR4
Small proline-rich protein 4; Cross-linked envelope protein of keratinocytes. Involved in UV-induced cornification; Belongs to the cornifin (SPRR) family (79 aa)
      
   
  0.739
LELP1
Late cornified envelope like proline rich 1; Belongs to the cornifin (SPRR) family (98 aa)
            
  0.732
S100A3
Protein S100-A3; Binds both calcium and zinc. May be involved in calcium- dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation; S100 calcium binding proteins (101 aa)
            
  0.727
S100A4
S100 calcium binding protein A4; EF-hand domain containing (101 aa)
            
  0.664
KPRP
Keratinocyte proline rich protein (579 aa)
      
   
  0.662
S100A7
S100 calcium binding protein A7; EF-hand domain containing (101 aa)
      
   
  0.645
LCE3E
Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum (92 aa)
            
  0.615
LINGO4
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4; Leucine rich repeat and Ig domain containing 4 (593 aa)
            
  0.609
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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