node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1orf43 | CRCT1 | ENSP00000357507 | ENSP00000357779 | Uncharacterized protein C1orf43; Chromosome 1 open reading frame 43 | Cysteine rich C-terminal 1 | 0.700 |
C1orf43 | S100A7A | ENSP00000357507 | ENSP00000357718 | Uncharacterized protein C1orf43; Chromosome 1 open reading frame 43 | Protein S100-A7A; May be involved in epidermal differentiation and inflammation and might therefore be important for the pathogenesis of psoriasis and other diseases; EF-hand domain containing | 0.668 |
C1orf43 | UBAP2L | ENSP00000357507 | ENSP00000389445 | Uncharacterized protein C1orf43; Chromosome 1 open reading frame 43 | Ubiquitin-associated protein 2-like; Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs) | 0.450 |
CRCT1 | C1orf43 | ENSP00000357779 | ENSP00000357507 | Cysteine rich C-terminal 1 | Uncharacterized protein C1orf43; Chromosome 1 open reading frame 43 | 0.700 |
CRCT1 | CRNN | ENSP00000357779 | ENSP00000271835 | Cysteine rich C-terminal 1 | Cornulin; Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest; Belongs to the S100-fused protein family | 0.660 |
CRCT1 | FAM25A | ENSP00000357779 | ENSP00000342790 | Cysteine rich C-terminal 1 | Family with sequence similarity 25 member A; Belongs to the FAM25 family | 0.680 |
CRCT1 | LCE2B | ENSP00000357779 | ENSP00000357769 | Cysteine rich C-terminal 1 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum | 0.682 |
CRCT1 | LCE3E | ENSP00000357779 | ENSP00000357778 | Cysteine rich C-terminal 1 | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum | 0.677 |
CRCT1 | S100A7A | ENSP00000357779 | ENSP00000357718 | Cysteine rich C-terminal 1 | Protein S100-A7A; May be involved in epidermal differentiation and inflammation and might therefore be important for the pathogenesis of psoriasis and other diseases; EF-hand domain containing | 0.694 |
CRCT1 | SPRR1A | ENSP00000357779 | ENSP00000357751 | Cysteine rich C-terminal 1 | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Small proline rich proteins | 0.661 |
CRCT1 | SPRR1B | ENSP00000357779 | ENSP00000306461 | Cysteine rich C-terminal 1 | Cornifin-B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross- linkage; Belongs to the cornifin (SPRR) family | 0.723 |
CRCT1 | SPRR3 | ENSP00000357779 | ENSP00000330391 | Cysteine rich C-terminal 1 | Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes; Small proline rich proteins | 0.702 |
CRCT1 | UBAP2L | ENSP00000357779 | ENSP00000389445 | Cysteine rich C-terminal 1 | Ubiquitin-associated protein 2-like; Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs) | 0.668 |
CRNN | CRCT1 | ENSP00000271835 | ENSP00000357779 | Cornulin; Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest; Belongs to the S100-fused protein family | Cysteine rich C-terminal 1 | 0.660 |
CRNN | SPRR1B | ENSP00000271835 | ENSP00000306461 | Cornulin; Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest; Belongs to the S100-fused protein family | Cornifin-B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross- linkage; Belongs to the cornifin (SPRR) family | 0.446 |
CRNN | SPRR3 | ENSP00000271835 | ENSP00000330391 | Cornulin; Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest; Belongs to the S100-fused protein family | Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes; Small proline rich proteins | 0.646 |
FAM25A | CRCT1 | ENSP00000342790 | ENSP00000357779 | Family with sequence similarity 25 member A; Belongs to the FAM25 family | Cysteine rich C-terminal 1 | 0.680 |
FAM25A | SPRR1A | ENSP00000342790 | ENSP00000357751 | Family with sequence similarity 25 member A; Belongs to the FAM25 family | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Small proline rich proteins | 0.565 |
LCE2B | CRCT1 | ENSP00000357769 | ENSP00000357779 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum | Cysteine rich C-terminal 1 | 0.682 |
LCE2B | LCE3E | ENSP00000357769 | ENSP00000357778 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum | 0.938 |