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  • 11.0 [archived version]
STRINGSTRING
SPRR2B SPRR2B LCE3E LCE3E LCE2C LCE2C LCE2D LCE2D LCE3D LCE3D SPRR2A SPRR2A SPRR2G SPRR2G LCE3A LCE3A LCE2B LCE2B LCE2A LCE2A IVL IVL
"LCE3D" - Late cornified envelope protein 3D in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCE3DLate cornified envelope protein 3D; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (92 aa)    
Predicted Functional Partners:
SPRR2G
Small proline-rich protein 2G; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity); Small proline rich proteins (73 aa)
     
 
  0.980
SPRR2B
Small proline-rich protein 2B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Small proline rich proteins (72 aa)
     
 
  0.977
LCE2C
Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum (110 aa)
     
  0.977
LCE3A
Late cornified envelope protein 3A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (89 aa)
     
 
  0.976
LCE2B
Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum (110 aa)
     
  0.974
LCE2D
Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum (110 aa)
     
 
  0.974
LCE3E
Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum (92 aa)
     
 
0.966
SPRR2A
Small proline-rich protein 2A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Belongs to the cornifin (SPRR) family (72 aa)
     
 
  0.962
LCE2A
Late cornified envelope protein 2A; Precursors of the cornified envelope of the stratum corneum (106 aa)
     
 
  0.961
IVL
Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family (585 aa)
     
 
  0.960
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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