• Version:
  • 11.0 [archived version]
STRINGSTRING
SPRR2G SPRR2G LCE3E LCE3E LCE2C LCE2C LCE2D LCE2D LCE3D LCE3D SPRR2F SPRR2F LOR LOR SPRR3 SPRR3 LCE2B LCE2B SPRR2D SPRR2D SPRR2E SPRR2E
"SPRR2G" - Small proline-rich protein 2G in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
SPRR2GSmall proline-rich protein 2G; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity); Small proline rich proteins (73 aa)    
Predicted Functional Partners:
LCE3D
Late cornified envelope protein 3D; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (92 aa)
     
 
  0.980
LCE3E
Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum (92 aa)
     
 
  0.977
SPRR2E
Small proline-rich protein 2E; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Small proline rich proteins (72 aa)
     
 
  0.974
LCE2C
Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum (110 aa)
     
 
  0.966
LCE2D
Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum (110 aa)
     
 
  0.961
LCE2B
Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum (110 aa)
     
 
  0.958
SPRR2D
Small proline-rich protein 2D; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Small proline rich proteins (72 aa)
     
 
  0.958
SPRR3
Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes; Small proline rich proteins (169 aa)
     
 
  0.954
SPRR2F
Small proline-rich protein 2F; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity); Small proline rich proteins (72 aa)
     
 
  0.954
LOR
Loricrin; Major keratinocyte cell envelope protein; Cornified envelope precursor family (312 aa)
     
 
  0.953
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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