LELP1 protein (human) - STRING database

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Score

LELP1

Late cornified envelope like proline rich 1; Belongs to the cornifin (SPRR) family (98 aa)

Predicted Functional Partners:

SPRR1A

0.963

SPRR1B

0.950

SPRR3

0.945

IVL

0.937

RPTN

0.935

TCHH

0.934

LCE3B

0.916

LCE2B

0.916

LOR

0.914

LCE3C

0.912

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IVL	LCE2B	ENSP00000357753	ENSP00000357769	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum	0.949
IVL	LCE3B	ENSP00000357753	ENSP00000335358	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Late cornified envelope protein 3B; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family	0.955
IVL	LCE3C	ENSP00000357753	ENSP00000334644	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Late cornified envelope protein 3C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family	0.951
IVL	LELP1	ENSP00000357753	ENSP00000357736	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Late cornified envelope like proline rich 1; Belongs to the cornifin (SPRR) family	0.937
IVL	LOR	ENSP00000357753	ENSP00000357731	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Loricrin; Major keratinocyte cell envelope protein; Cornified envelope precursor family	0.993
IVL	RPTN	ENSP00000357753	ENSP00000317895	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Repetin; Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium; EF-hand domain containing	0.961
IVL	SPRR1A	ENSP00000357753	ENSP00000357751	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Small proline rich proteins	0.985
IVL	SPRR1B	ENSP00000357753	ENSP00000306461	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Cornifin-B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross- linkage; Belongs to the cornifin (SPRR) family	0.984
IVL	SPRR3	ENSP00000357753	ENSP00000330391	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes; Small proline rich proteins	0.985
IVL	TCHH	ENSP00000357753	ENSP00000480484	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	Trichohyalin; Intermediate filament-associated protein that associates in regular arrays with keratin intermediate filaments (KIF) of the inner root sheath cells of the hair follicle and the granular layer of the epidermis. It later becomes cross-linked to KIF by isodipeptide bonds. It may serve as scaffold protein, together with involucrin, in the organization of the cell envelope or even anchor the cell envelope to the KIF network. It may be involved in its own calcium-dependent postsynthetic processing during terminal differentiation; EF-hand domain containing	0.974
LCE2B	IVL	ENSP00000357769	ENSP00000357753	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum	Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia; Belongs to the involucrin family	0.949
LCE2B	LCE3B	ENSP00000357769	ENSP00000335358	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum	Late cornified envelope protein 3B; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family	0.941
LCE2B	LCE3C	ENSP00000357769	ENSP00000334644	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum	Late cornified envelope protein 3C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family	0.912
LCE2B	LELP1	ENSP00000357769	ENSP00000357736	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum	Late cornified envelope like proline rich 1; Belongs to the cornifin (SPRR) family	0.916
LCE2B	LOR	ENSP00000357769	ENSP00000357731	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum	Loricrin; Major keratinocyte cell envelope protein; Cornified envelope precursor family	0.959
LCE2B	RPTN	ENSP00000357769	ENSP00000317895	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum	Repetin; Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium; EF-hand domain containing	0.929
LCE2B	SPRR1A	ENSP00000357769	ENSP00000357751	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum	Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Small proline rich proteins	0.941
LCE2B	SPRR1B	ENSP00000357769	ENSP00000306461	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum	Cornifin-B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross- linkage; Belongs to the cornifin (SPRR) family	0.946
LCE2B	SPRR3	ENSP00000357769	ENSP00000330391	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum	Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes; Small proline rich proteins	0.943
LCE2B	TCHH	ENSP00000357769	ENSP00000480484	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum	Trichohyalin; Intermediate filament-associated protein that associates in regular arrays with keratin intermediate filaments (KIF) of the inner root sheath cells of the hair follicle and the granular layer of the epidermis. It later becomes cross-linked to KIF by isodipeptide bonds. It may serve as scaffold protein, together with involucrin, in the organization of the cell envelope or even anchor the cell envelope to the KIF network. It may be involved in its own calcium-dependent postsynthetic processing during terminal differentiation; EF-hand domain containing	0.925

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