• Version:
  • 11.0 [archived version]
STRINGSTRING
FLG2 FLG2 S100A7A S100A7A SPRR4 SPRR4 TCHHL1 TCHHL1 S100A7 S100A7 S100A7L2 S100A7L2 LELP1 LELP1 S100A3 S100A3 HRNR HRNR RPTN RPTN S100Z S100Z
"S100A7L2" - S100 calcium binding protein A7 like 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
S100A7L2S100 calcium binding protein A7 like 2; EF-hand domain containing (112 aa)    
Predicted Functional Partners:
TCHHL1
S100 fused type protein family; Belongs to the S-100 family (904 aa)
     
   
  0.778
LELP1
Late cornified envelope like proline rich 1; Belongs to the cornifin (SPRR) family (98 aa)
     
   
  0.720
SPRR4
Small proline-rich protein 4; Cross-linked envelope protein of keratinocytes. Involved in UV-induced cornification; Belongs to the cornifin (SPRR) family (79 aa)
     
   
  0.693
FLG2
Filaggrin-2; S100 fused type protein family; In the N-terminal section; belongs to the S-100 family (2391 aa)
           
  0.608
S100A3
Protein S100-A3; Binds both calcium and zinc. May be involved in calcium- dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation; S100 calcium binding proteins (101 aa)
           
  0.591
S100Z
S100 calcium binding protein Z; EF-hand domain containing (99 aa)
           
  0.590
RPTN
Repetin; Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium; EF-hand domain containing (784 aa)
     
   
  0.565
S100A7
S100 calcium binding protein A7; EF-hand domain containing (101 aa)
       
 
0.558
S100A7A
Protein S100-A7A; May be involved in epidermal differentiation and inflammation and might therefore be important for the pathogenesis of psoriasis and other diseases; EF-hand domain containing (101 aa)
       
 
0.547
HRNR
Hornerin; Component of the epidermal cornified cell envelopes; Belongs to the S100-fused protein family (2850 aa)
           
  0.542
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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