| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CFAP45 | FANK1 | ENSP00000357079 | ENSP00000357682 | Cilia and flagella associated protein 45; Belongs to the CFAP45 family | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | 0.596 |
| CFAP45 | LRRIQ1 | ENSP00000357079 | ENSP00000376910 | Cilia and flagella associated protein 45; Belongs to the CFAP45 family | Leucine rich repeats and IQ motif containing 1 | 0.662 |
| CFAP45 | TTC18 | ENSP00000357079 | ENSP00000310829 | Cilia and flagella associated protein 45; Belongs to the CFAP45 family | Cilia- and flagella-associated protein 70; Tetratricopeptide repeat domain 18; Belongs to the CFAP70 family | 0.663 |
| CFAP45 | WDR16 | ENSP00000357079 | ENSP00000339449 | Cilia and flagella associated protein 45; Belongs to the CFAP45 family | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival | 0.685 |
| COPS5 | FANK1 | ENSP00000350512 | ENSP00000357682 | COP9 signalosome complex subunit 5; Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD [...] | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | 0.748 |
| CYB5R2 | FANK1 | ENSP00000437041 | ENSP00000357682 | NADH-cytochrome b5 reductase 2; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4- disulfophenyl]-2H tetrazolium monosodium salt (WST-1); Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | 0.710 |
| FANK1 | CFAP45 | ENSP00000357682 | ENSP00000357079 | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | Cilia and flagella associated protein 45; Belongs to the CFAP45 family | 0.596 |
| FANK1 | COPS5 | ENSP00000357682 | ENSP00000350512 | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | COP9 signalosome complex subunit 5; Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD [...] | 0.748 |
| FANK1 | CYB5R2 | ENSP00000357682 | ENSP00000437041 | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | NADH-cytochrome b5 reductase 2; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4- disulfophenyl]-2H tetrazolium monosodium salt (WST-1); Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family | 0.710 |
| FANK1 | HSD17B13 | ENSP00000357682 | ENSP00000333300 | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | 17-beta-hydroxysteroid dehydrogenase 13; Short chain dehydrogenase/reductase superfamily | 0.590 |
| FANK1 | LRRIQ1 | ENSP00000357682 | ENSP00000376910 | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | Leucine rich repeats and IQ motif containing 1 | 0.642 |
| FANK1 | RYBP | ENSP00000357682 | ENSP00000419494 | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | RING1 and YY1-binding protein; Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1-like complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ’Lys-119’, rendering chromatin heritably changed in its expressibility. Component of a PRC1-like complex that mediates monoubiquitination of histone H2A ’Lys-119’ on the X chromosome and is required for normal silencing of one c [...] | 0.736 |
| FANK1 | SPATA4 | ENSP00000357682 | ENSP00000280191 | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | Spermatogenesis-associated protein 4; Spermatogenesis associated 4 | 0.735 |
| FANK1 | TCTA | ENSP00000357682 | ENSP00000273590 | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | T-cell leukemia translocation-altered gene protein; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family | 0.612 |
| FANK1 | TTC18 | ENSP00000357682 | ENSP00000310829 | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | Cilia- and flagella-associated protein 70; Tetratricopeptide repeat domain 18; Belongs to the CFAP70 family | 0.665 |
| FANK1 | WDR16 | ENSP00000357682 | ENSP00000339449 | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival | 0.598 |
| HSD17B13 | FANK1 | ENSP00000333300 | ENSP00000357682 | 17-beta-hydroxysteroid dehydrogenase 13; Short chain dehydrogenase/reductase superfamily | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | 0.590 |
| LRRIQ1 | CFAP45 | ENSP00000376910 | ENSP00000357079 | Leucine rich repeats and IQ motif containing 1 | Cilia and flagella associated protein 45; Belongs to the CFAP45 family | 0.662 |
| LRRIQ1 | FANK1 | ENSP00000376910 | ENSP00000357682 | Leucine rich repeats and IQ motif containing 1 | Fibronectin type 3 and ankyrin repeat domains protein 1; Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis; Ankyrin repeat domain containing | 0.642 |
| LRRIQ1 | TTC18 | ENSP00000376910 | ENSP00000310829 | Leucine rich repeats and IQ motif containing 1 | Cilia- and flagella-associated protein 70; Tetratricopeptide repeat domain 18; Belongs to the CFAP70 family | 0.732 |
