node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B3GALT2 | FAM229B | ENSP00000356404 | ENSP00000357645 | Beta-1,3-galactosyltransferase 2; Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues | Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family | 0.667 |
B3GALT2 | IQCF1 | ENSP00000356404 | ENSP00000307958 | Beta-1,3-galactosyltransferase 2; Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction | 0.545 |
B3GALT2 | OR2AK2 | ENSP00000356404 | ENSP00000355436 | Beta-1,3-galactosyltransferase 2; Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues | Olfactory receptor 2AK2; Odorant receptor; Olfactory receptors, family 2 | 0.426 |
B3GALT2 | TMEM60 | ENSP00000356404 | ENSP00000257663 | Beta-1,3-galactosyltransferase 2; Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues | Transmembrane protein 60 | 0.487 |
DENR | FAM229B | ENSP00000280557 | ENSP00000357645 | Density-regulated protein; May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 | Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family | 0.539 |
FAM229B | B3GALT2 | ENSP00000357645 | ENSP00000356404 | Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family | Beta-1,3-galactosyltransferase 2; Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues | 0.667 |
FAM229B | DENR | ENSP00000357645 | ENSP00000280557 | Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family | Density-regulated protein; May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 | 0.539 |
FAM229B | GPR37 | ENSP00000357645 | ENSP00000306449 | Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family | Prosaposin receptor GPR37; Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade; Belongs to the G-protein coupled receptor 1 family | 0.534 |
FAM229B | IQCF1 | ENSP00000357645 | ENSP00000307958 | Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction | 0.799 |
FAM229B | NPIPB9 | ENSP00000357645 | ENSP00000446902 | Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family | Nuclear pore complex interacting protein family member B9; Belongs to the NPIP family | 0.740 |
FAM229B | OR2AK2 | ENSP00000357645 | ENSP00000355436 | Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family | Olfactory receptor 2AK2; Odorant receptor; Olfactory receptors, family 2 | 0.700 |
FAM229B | TAS2R13 | ENSP00000357645 | ENSP00000375095 | Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family | Taste receptor type 2 member 13; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5; Belongs to the G-protein coupled receptor T2R family | 0.635 |
FAM229B | TMEM60 | ENSP00000357645 | ENSP00000257663 | Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family | Transmembrane protein 60 | 0.780 |
GPR37 | FAM229B | ENSP00000306449 | ENSP00000357645 | Prosaposin receptor GPR37; Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade; Belongs to the G-protein coupled receptor 1 family | Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family | 0.534 |
GPR37 | IQCF1 | ENSP00000306449 | ENSP00000307958 | Prosaposin receptor GPR37; Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade; Belongs to the G-protein coupled receptor 1 family | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction | 0.407 |
GPR37 | TAS2R13 | ENSP00000306449 | ENSP00000375095 | Prosaposin receptor GPR37; Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade; Belongs to the G-protein coupled receptor 1 family | Taste receptor type 2 member 13; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5; Belongs to the G-protein coupled receptor T2R family | 0.915 |
IQCF1 | B3GALT2 | ENSP00000307958 | ENSP00000356404 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction | Beta-1,3-galactosyltransferase 2; Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues | 0.545 |
IQCF1 | FAM229B | ENSP00000307958 | ENSP00000357645 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction | Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family | 0.799 |
IQCF1 | GPR37 | ENSP00000307958 | ENSP00000306449 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction | Prosaposin receptor GPR37; Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade; Belongs to the G-protein coupled receptor 1 family | 0.407 |
IQCF1 | NPIPB9 | ENSP00000307958 | ENSP00000446902 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction | Nuclear pore complex interacting protein family member B9; Belongs to the NPIP family | 0.473 |