node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C12orf55 | CFAP221 | ENSP00000431759 | ENSP00000393222 | Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated | 0.771 |
C12orf55 | CFAP46 | ENSP00000431759 | ENSP00000357575 | Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | 0.813 |
C19orf81 | CFAP46 | ENSP00000417035 | ENSP00000357575 | Putative uncharacterized protein C19orf81; Chromosome 19 open reading frame 81 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | 0.701 |
C19orf81 | CXorf58 | ENSP00000417035 | ENSP00000368511 | Putative uncharacterized protein C19orf81; Chromosome 19 open reading frame 81 | Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58 | 0.860 |
CFAP221 | C12orf55 | ENSP00000393222 | ENSP00000431759 | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated | Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella | 0.771 |
CFAP221 | CFAP46 | ENSP00000393222 | ENSP00000357575 | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | 0.758 |
CFAP221 | PACRG | ENSP00000393222 | ENSP00000337946 | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease; Armadillo-like helical domain containing | 0.666 |
CFAP46 | C12orf55 | ENSP00000357575 | ENSP00000431759 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella | 0.813 |
CFAP46 | C19orf81 | ENSP00000357575 | ENSP00000417035 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | Putative uncharacterized protein C19orf81; Chromosome 19 open reading frame 81 | 0.701 |
CFAP46 | CFAP221 | ENSP00000357575 | ENSP00000393222 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated | 0.758 |
CFAP46 | CXorf58 | ENSP00000357575 | ENSP00000368511 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58 | 0.707 |
CFAP46 | DNAH10 | ENSP00000357575 | ENSP00000386770 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain | 0.775 |
CFAP46 | DNAH2 | ENSP00000357575 | ENSP00000458355 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | Dynein heavy chain 2, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity); Dyneins, axonemal | 0.645 |
CFAP46 | ERMARD | ENSP00000357575 | ENSP00000355735 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | Endoplasmic reticulum membrane-associated RNA degradation protein; May play a role in neuronal migration during embryonic development | 0.747 |
CFAP46 | NPIPB11 | ENSP00000357575 | ENSP00000430853 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | Nuclear pore complex interacting protein family member B11 | 0.675 |
CFAP46 | PACRG | ENSP00000357575 | ENSP00000337946 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease; Armadillo-like helical domain containing | 0.732 |
CFAP46 | RNF115 | ENSP00000357575 | ENSP00000463650 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | E3 ubiquitin-protein ligase RNF115; E3 ubiquitin-protein ligase that mediates E2-dependent, ’Lys-48’- and/or ’Lys-63’-linked polyubiquitination of substrates and may play a role in diverse biological processes. Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4; Ring finger proteins | 0.746 |
CXorf58 | C19orf81 | ENSP00000368511 | ENSP00000417035 | Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58 | Putative uncharacterized protein C19orf81; Chromosome 19 open reading frame 81 | 0.860 |
CXorf58 | CFAP46 | ENSP00000368511 | ENSP00000357575 | Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58 | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | 0.707 |
DNAH10 | CFAP46 | ENSP00000386770 | ENSP00000357575 | Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain | Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated | 0.775 |