node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCHCR1 | FCRL6 | ENSP00000379566 | ENSP00000357086 | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | 0.562 |
CCHCR1 | ICE2 | ENSP00000379566 | ENSP00000261520 | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | Little elongation complex subunit 2; Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III; Belongs to the ICE2 family | 0.560 |
CFAP45 | FCRL6 | ENSP00000357079 | ENSP00000357086 | Cilia and flagella associated protein 45; Belongs to the CFAP45 family | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | 0.582 |
CFAP45 | FRMD5 | ENSP00000357079 | ENSP00000403067 | Cilia and flagella associated protein 45; Belongs to the CFAP45 family | FERM domain-containing protein 5; May be involved in regulation of cell migration. May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation; FERM domain containing | 0.649 |
CFAP45 | SLAMF8 | ENSP00000357079 | ENSP00000289707 | Cilia and flagella associated protein 45; Belongs to the CFAP45 family | SLAM family member 8; May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor; CD molecules | 0.495 |
CFAP45 | WDR76 | ENSP00000357079 | ENSP00000263795 | Cilia and flagella associated protein 45; Belongs to the CFAP45 family | WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC; WD repeat domain containing | 0.585 |
FAM167B | FCRL6 | ENSP00000362684 | ENSP00000357086 | Protein FAM167B; Family with sequence similarity 167 member B; Belongs to the FAM167 (SEC) family | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | 0.766 |
FAM167B | STK33 | ENSP00000362684 | ENSP00000416750 | Protein FAM167B; Family with sequence similarity 167 member B; Belongs to the FAM167 (SEC) family | Serine/threonine-protein kinase 33; Serine/threonine protein kinase which phosphorylates VIME. May play a specific role in the dynamic behavior of the intermediate filament cytoskeleton by phosphorylation of VIME (By similarity). Not essential for the survival of KRAS-dependent AML cell lines | 0.800 |
FCRL6 | CCHCR1 | ENSP00000357086 | ENSP00000379566 | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | 0.562 |
FCRL6 | CFAP45 | ENSP00000357086 | ENSP00000357079 | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | Cilia and flagella associated protein 45; Belongs to the CFAP45 family | 0.582 |
FCRL6 | FAM167B | ENSP00000357086 | ENSP00000362684 | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | Protein FAM167B; Family with sequence similarity 167 member B; Belongs to the FAM167 (SEC) family | 0.766 |
FCRL6 | FRMD5 | ENSP00000357086 | ENSP00000403067 | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | FERM domain-containing protein 5; May be involved in regulation of cell migration. May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation; FERM domain containing | 0.577 |
FCRL6 | ICE2 | ENSP00000357086 | ENSP00000261520 | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | Little elongation complex subunit 2; Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III; Belongs to the ICE2 family | 0.576 |
FCRL6 | LY6G6C | ENSP00000357086 | ENSP00000364978 | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | Lymphocyte antigen 6 family member G6C; LY6/PLAUR domain containing | 0.651 |
FCRL6 | PDZK1IP1 | ENSP00000357086 | ENSP00000294338 | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | PDZK1-interacting protein 1; May play an important role in tumor biology | 0.526 |
FCRL6 | SLAMF8 | ENSP00000357086 | ENSP00000289707 | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | SLAM family member 8; May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor; CD molecules | 0.654 |
FCRL6 | STK33 | ENSP00000357086 | ENSP00000416750 | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | Serine/threonine-protein kinase 33; Serine/threonine protein kinase which phosphorylates VIME. May play a specific role in the dynamic behavior of the intermediate filament cytoskeleton by phosphorylation of VIME (By similarity). Not essential for the survival of KRAS-dependent AML cell lines | 0.631 |
FCRL6 | WDR76 | ENSP00000357086 | ENSP00000263795 | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC; WD repeat domain containing | 0.563 |
FRMD5 | CFAP45 | ENSP00000403067 | ENSP00000357079 | FERM domain-containing protein 5; May be involved in regulation of cell migration. May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation; FERM domain containing | Cilia and flagella associated protein 45; Belongs to the CFAP45 family | 0.649 |
FRMD5 | FCRL6 | ENSP00000403067 | ENSP00000357086 | FERM domain-containing protein 5; May be involved in regulation of cell migration. May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation; FERM domain containing | Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing | 0.577 |