• Version:
  • 11.0 [archived version]
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FCRL6 FCRL6 CFAP45 CFAP45 SLAMF8 SLAMF8 SULT2B1 SULT2B1 TAGLN2 TAGLN2 IGSF9 IGSF9 PTCHD3 PTCHD3 FOXN3 FOXN3 UBLCP1 UBLCP1 MEX3A MEX3A VSIG2 VSIG2
"IGSF9" - Protein turtle homolog A in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
IGSF9Protein turtle homolog A; Functions in dendrite outgrowth and synapse maturation; Belongs to the immunoglobulin superfamily. Turtle family (1179 aa)    
Predicted Functional Partners:
UBLCP1
Ubiquitin-like domain-containing CTD phosphatase 1; Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome; CTD family phosphatases (318 aa)
           
  0.728
PTCHD3
Patched domain-containing protein 3; May play a role in sperm development or sperm function (767 aa)
           
  0.723
SLAMF8
SLAM family member 8; May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor; CD molecules (285 aa)
           
  0.713
FOXN3
Forkhead box protein N3; Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints); Forkhead boxes (490 aa)
           
  0.652
CFAP45
Cilia and flagella associated protein 45; Belongs to the CFAP45 family (551 aa)
     
   
  0.543
MEX3A
RNA-binding protein MEX3A; RNA binding protein, may be involved in post- transcriptional regulatory mechanisms; Ring finger proteins (520 aa)
     
   
  0.536
FCRL6
Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing (434 aa)
           
  0.517
TAGLN2
Transgelin-2; Transgelin 2 (220 aa)
           
  0.511
SULT2B1
Sulfotransferase family cytosolic 2B member 1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. Plays a role in epidermal choleste [...] (365 aa)
           
  0.503
VSIG2
V-set and immunoglobulin domain containing 2 (327 aa)
           
  0.500
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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