• Version:
  • 11.0 [archived version]
STRINGSTRING
DNAJC11 DNAJC11 RFESD RFESD HAPLN3 HAPLN3 BLZF1 BLZF1 NME7 NME7 MOB3B MOB3B CCDC181 CCDC181 C1orf112 C1orf112 METTL18 METTL18 CCDC148 CCDC148 LRRC49 LRRC49
"CCDC181" - Coiled-coil domain-containing protein 181 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CCDC181Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids; Belongs to the CCDC181 family (509 aa)    
Predicted Functional Partners:
BLZF1
Golgin-45; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface (400 aa)
           
  0.857
CCDC148
Coiled-coil domain containing 148 (591 aa)
     
   
  0.751
NME7
Nucleoside diphosphate kinase 7; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Cilia and flagella associated (376 aa)
           
  0.745
LRRC49
Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49 (691 aa)
     
   
  0.725
METTL18
Histidine protein methyltransferase 1 homolog; Probable histidine methyltransferase (372 aa)
           
  0.693
RFESD
Rieske domain-containing protein; Rieske Fe-S domain containing (210 aa)
           
  0.690
HAPLN3
Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding; V-set domain containing (360 aa)
           
  0.679
DNAJC11
DnaJ homolog subfamily C member 11; Isoform 1- Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family (559 aa)
           
  0.670
MOB3B
MOB kinase activator 3B; May regulate the activity of kinases; MOB kinase activators (216 aa)
           
  0.668
C1orf112
Uncharacterized protein C1orf112; Chromosome 1 open reading frame 112 (853 aa)
           
  0.626
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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