| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DARS2 | OSBPL9 | ENSP00000355086 | ENSP00000412733 | Aspartate--tRNA ligase, mitochondrial; aspartyl-tRNA synthetase 2, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily | Oxysterol-binding protein-related protein 9; Pleckstrin homology domain containing; Belongs to the OSBP family | 0.692 |
| DARS2 | RHOF | ENSP00000355086 | ENSP00000267205 | Aspartate--tRNA ligase, mitochondrial; aspartyl-tRNA synthetase 2, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily | Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin- based morphology; Rho family GTPases | 0.641 |
| DARS2 | SETD1B | ENSP00000355086 | ENSP00000442924 | Aspartate--tRNA ligase, mitochondrial; aspartyl-tRNA synthetase 2, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily | Histone-lysine N-methyltransferase SETD1B; Histone methyltransferase that specifically methylates ’Lys-4’ of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring ’Lys- 9’ residue is already methylated. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. The non-overlapping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates ’Lys-4’ of histone H3 in vitro; Belongs t [...] | 0.656 |
| DARS2 | TOR3A | ENSP00000355086 | ENSP00000356599 | Aspartate--tRNA ligase, mitochondrial; aspartyl-tRNA synthetase 2, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily | Torsin-3A; Minor histocompatibility antigens | 0.673 |
| DARS2 | ZBTB37 | ENSP00000355086 | ENSP00000356674 | Aspartate--tRNA ligase, mitochondrial; aspartyl-tRNA synthetase 2, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily | Zinc finger and BTB domain-containing protein 37; May be involved in transcriptional regulation; BTB domain containing | 0.777 |
| FMR1 | TOR3A | ENSP00000359506 | ENSP00000356599 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export (By similarity). Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons (By similarity). Stabilizes the scaffolding postsyna [...] | Torsin-3A; Minor histocompatibility antigens | 0.612 |
| MRPS18A | RFT1 | ENSP00000361206 | ENSP00000296292 | Mitochondrial ribosomal protein S18A; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily | Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane | 0.404 |
| MRPS18A | TOR3A | ENSP00000361206 | ENSP00000356599 | Mitochondrial ribosomal protein S18A; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily | Torsin-3A; Minor histocompatibility antigens | 0.640 |
| OSBPL9 | DARS2 | ENSP00000412733 | ENSP00000355086 | Oxysterol-binding protein-related protein 9; Pleckstrin homology domain containing; Belongs to the OSBP family | Aspartate--tRNA ligase, mitochondrial; aspartyl-tRNA synthetase 2, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily | 0.692 |
| OSBPL9 | RHOF | ENSP00000412733 | ENSP00000267205 | Oxysterol-binding protein-related protein 9; Pleckstrin homology domain containing; Belongs to the OSBP family | Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin- based morphology; Rho family GTPases | 0.654 |
| OSBPL9 | SETD1B | ENSP00000412733 | ENSP00000442924 | Oxysterol-binding protein-related protein 9; Pleckstrin homology domain containing; Belongs to the OSBP family | Histone-lysine N-methyltransferase SETD1B; Histone methyltransferase that specifically methylates ’Lys-4’ of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring ’Lys- 9’ residue is already methylated. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. The non-overlapping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates ’Lys-4’ of histone H3 in vitro; Belongs t [...] | 0.659 |
| OSBPL9 | TOR3A | ENSP00000412733 | ENSP00000356599 | Oxysterol-binding protein-related protein 9; Pleckstrin homology domain containing; Belongs to the OSBP family | Torsin-3A; Minor histocompatibility antigens | 0.675 |
| OSBPL9 | ZBTB37 | ENSP00000412733 | ENSP00000356674 | Oxysterol-binding protein-related protein 9; Pleckstrin homology domain containing; Belongs to the OSBP family | Zinc finger and BTB domain-containing protein 37; May be involved in transcriptional regulation; BTB domain containing | 0.788 |
| RFT1 | MRPS18A | ENSP00000296292 | ENSP00000361206 | Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane | Mitochondrial ribosomal protein S18A; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily | 0.404 |
| RFT1 | TOR3A | ENSP00000296292 | ENSP00000356599 | Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane | Torsin-3A; Minor histocompatibility antigens | 0.714 |
| RHOF | DARS2 | ENSP00000267205 | ENSP00000355086 | Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin- based morphology; Rho family GTPases | Aspartate--tRNA ligase, mitochondrial; aspartyl-tRNA synthetase 2, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily | 0.641 |
| RHOF | OSBPL9 | ENSP00000267205 | ENSP00000412733 | Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin- based morphology; Rho family GTPases | Oxysterol-binding protein-related protein 9; Pleckstrin homology domain containing; Belongs to the OSBP family | 0.654 |
| RHOF | SETD1B | ENSP00000267205 | ENSP00000442924 | Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin- based morphology; Rho family GTPases | Histone-lysine N-methyltransferase SETD1B; Histone methyltransferase that specifically methylates ’Lys-4’ of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring ’Lys- 9’ residue is already methylated. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. The non-overlapping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates ’Lys-4’ of histone H3 in vitro; Belongs t [...] | 0.597 |
| RHOF | TOR3A | ENSP00000267205 | ENSP00000356599 | Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin- based morphology; Rho family GTPases | Torsin-3A; Minor histocompatibility antigens | 0.643 |
| RHOF | ZBTB37 | ENSP00000267205 | ENSP00000356674 | Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin- based morphology; Rho family GTPases | Zinc finger and BTB domain-containing protein 37; May be involved in transcriptional regulation; BTB domain containing | 0.716 |
