AXDND1 protein (human) - STRING database

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AXDND1

Axonemal dynein light chain domain containing 1 (1012 aa)

Predicted Functional Partners:

C19orf81

0.763

CXorf58

0.737

CFAP46

0.631

PCDHA9

0.629

ENTHD1

0.522

TOR1AIP2

0.516

TOR1AIP1

0.510

CEP350

0.472

TDRD5

0.461

FBN3

0.448

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXDND1	C19orf81	ENSP00000356590	ENSP00000417035	Axonemal dynein light chain domain containing 1	Putative uncharacterized protein C19orf81; Chromosome 19 open reading frame 81	0.763
AXDND1	CEP350	ENSP00000356590	ENSP00000356579	Axonemal dynein light chain domain containing 1	Centrosome-associated protein 350; Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. Required for ciliation	0.472
AXDND1	CFAP46	ENSP00000356590	ENSP00000357575	Axonemal dynein light chain domain containing 1	Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated	0.631
AXDND1	CXorf58	ENSP00000356590	ENSP00000368511	Axonemal dynein light chain domain containing 1	Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58	0.737
AXDND1	ENTHD1	ENSP00000356590	ENSP00000317431	Axonemal dynein light chain domain containing 1	ENTH domain containing 1	0.522
AXDND1	FBN3	ENSP00000356590	ENSP00000470498	Axonemal dynein light chain domain containing 1	Fibrillin-3; Fibrillin-3- Fibrillins are structural components of 10- 12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-containing microfibrils provide long-term force bearing structural support; Belongs to the fibrillin family	0.448
AXDND1	PCDHA9	ENSP00000356590	ENSP00000436042	Axonemal dynein light chain domain containing 1	Protocadherin alpha-9; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	0.629
AXDND1	TDRD5	ENSP00000356590	ENSP00000406052	Axonemal dynein light chain domain containing 1	Tudor domain-containing protein 5; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity); Tudor domain containing	0.461
AXDND1	TOR1AIP1	ENSP00000356590	ENSP00000435365	Axonemal dynein light chain domain containing 1	Torsin-1A-interacting protein 1; Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina	0.510
AXDND1	TOR1AIP2	ENSP00000356590	ENSP00000356584	Axonemal dynein light chain domain containing 1	Torsin-1A-interacting protein 2; Required for endoplasmic reticulum integrity. Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope as well as induces TOR1A, TOR1B and TOR3A ATPase activity; Belongs to the TOR1AIP family	0.516
C19orf81	AXDND1	ENSP00000417035	ENSP00000356590	Putative uncharacterized protein C19orf81; Chromosome 19 open reading frame 81	Axonemal dynein light chain domain containing 1	0.763
C19orf81	CFAP46	ENSP00000417035	ENSP00000357575	Putative uncharacterized protein C19orf81; Chromosome 19 open reading frame 81	Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated	0.701
C19orf81	CXorf58	ENSP00000417035	ENSP00000368511	Putative uncharacterized protein C19orf81; Chromosome 19 open reading frame 81	Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58	0.860
CEP350	AXDND1	ENSP00000356579	ENSP00000356590	Centrosome-associated protein 350; Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. Required for ciliation	Axonemal dynein light chain domain containing 1	0.472
CEP350	TDRD5	ENSP00000356579	ENSP00000406052	Centrosome-associated protein 350; Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. Required for ciliation	Tudor domain-containing protein 5; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity); Tudor domain containing	0.454
CEP350	TOR1AIP1	ENSP00000356579	ENSP00000435365	Centrosome-associated protein 350; Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. Required for ciliation	Torsin-1A-interacting protein 1; Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina	0.595
CFAP46	AXDND1	ENSP00000357575	ENSP00000356590	Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated	Axonemal dynein light chain domain containing 1	0.631
CFAP46	C19orf81	ENSP00000357575	ENSP00000417035	Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated	Putative uncharacterized protein C19orf81; Chromosome 19 open reading frame 81	0.701
CFAP46	CXorf58	ENSP00000357575	ENSP00000368511	Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement; Cilia and flagella associated	Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58	0.707
CXorf58	AXDND1	ENSP00000368511	ENSP00000356590	Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58	Axonemal dynein light chain domain containing 1	0.737

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