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STRINGSTRING
TPBGL TPBGL PRKCZ PRKCZ KIAA2012 KIAA2012 PRKCI PRKCI EFCAB5 EFCAB5 EXOC3L4 EXOC3L4 KIAA1614 KIAA1614 FAM186A FAM186A C21orf58 C21orf58 FAM217B FAM217B RBBP8NL RBBP8NL
"KIAA1614" - Uncharacterized protein KIAA1614 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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KIAA1614Uncharacterized protein KIAA1614; KIAA1614 (1190 aa)    
Predicted Functional Partners:
PRKCZ
Protein kinase C zeta type; Calcium- and diacylglycerol-independent serine/threonine-protein kinase that functions in phosphatidylinositol 3-kinase (PI3K) pathway and mitogen-activated protein (MAP) kinase cascade, and is involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, inflammatory response and maintenance of long-term potentiation (LTP). Upon lipopolysaccharide (LPS) treatment in macrophages, or following mitogenic stimuli, functions downstream of PI3K to activate MAP2K1/MEK1-MAPK1/ERK2 signaling cascade independently of RAF1 activation. Requ [...] (592 aa)
      
 
  0.752
PRKCI
Protein kinase C iota type; Calcium- and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway. Is necessary for BCR-ABL oncogene-mediated resistance to apoptotic drug in leukemia cells, protecting leukemia cells against drug-induced apoptosis. In cultured neurons, prevents amyloid beta protein-induced apoptosis by interrupting cell death process a [...] (596 aa)
      
 
  0.752
KIAA2012
Uncharacterized protein KIAA2012 (1180 aa)
            
  0.652
TPBGL
Trophoblast glycoprotein like (382 aa)
            
  0.642
RBBP8NL
RBBP8 N-terminal-like protein; RBBP8 N-terminal like (664 aa)
            
  0.578
FAM217B
Protein FAM217B; Family with sequence similarity 217 member B; Belongs to the FAM217 family (383 aa)
            
  0.569
FAM186A
Protein FAM186A; Family with sequence similarity 186 member A; Belongs to the FAM186 family (2351 aa)
            
  0.553
C21orf58
Uncharacterized protein C21orf58; Chromosome 21 open reading frame 58 (322 aa)
            
  0.552
EXOC3L4
Exocyst complex component 3 like 4; Belongs to the SEC6 family (722 aa)
            
  0.533
EFCAB5
EF-hand calcium-binding domain-containing protein 5; EF-hand calcium binding domain 5 (1503 aa)
            
  0.529
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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