MTRF1L protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MTRF1L

Peptide chain release factor 1-like, mitochondrial; Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG (380 aa)

Predicted Functional Partners:

ICT1

0.988

MRPS7

0.981

MRPS16

0.979

MRRF

0.977

MRPL20

0.977

MRPL17

0.976

MRPL27

0.974

MRPL9

0.972

MRPS9

0.971

MRPL19

0.968

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ICT1	MRPL17	ENSP00000301585	ENSP00000288937	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein L17	0.997
ICT1	MRPL19	ENSP00000301585	ENSP00000377486	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family	0.999
ICT1	MRPL20	ENSP00000301585	ENSP00000341082	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein L20	0.998
ICT1	MRPL27	ENSP00000301585	ENSP00000225969	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein L27	0.997
ICT1	MRPL9	ENSP00000301585	ENSP00000357823	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein L9	0.996
ICT1	MRPS16	ENSP00000301585	ENSP00000362036	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family	0.998
ICT1	MRPS7	ENSP00000301585	ENSP00000245539	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein S7; Belongs to the universal ribosomal protein uS7 family	0.997
ICT1	MRPS9	ENSP00000301585	ENSP00000258455	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Mitochondrial ribosomal protein S9	0.996
ICT1	MRRF	ENSP00000301585	ENSP00000343867	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)	0.979
ICT1	MTRF1L	ENSP00000301585	ENSP00000356202	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	Peptide chain release factor 1-like, mitochondrial; Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG	0.988
MRPL17	ICT1	ENSP00000288937	ENSP00000301585	Mitochondrial ribosomal protein L17	Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	0.997
MRPL17	MRPL19	ENSP00000288937	ENSP00000377486	Mitochondrial ribosomal protein L17	Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family	0.999
MRPL17	MRPL20	ENSP00000288937	ENSP00000341082	Mitochondrial ribosomal protein L17	Mitochondrial ribosomal protein L20	0.998
MRPL17	MRPL27	ENSP00000288937	ENSP00000225969	Mitochondrial ribosomal protein L17	Mitochondrial ribosomal protein L27	0.999
MRPL17	MRPL9	ENSP00000288937	ENSP00000357823	Mitochondrial ribosomal protein L17	Mitochondrial ribosomal protein L9	0.999
MRPL17	MRPS16	ENSP00000288937	ENSP00000362036	Mitochondrial ribosomal protein L17	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family	0.999
MRPL17	MRPS7	ENSP00000288937	ENSP00000245539	Mitochondrial ribosomal protein L17	Mitochondrial ribosomal protein S7; Belongs to the universal ribosomal protein uS7 family	0.999
MRPL17	MRPS9	ENSP00000288937	ENSP00000258455	Mitochondrial ribosomal protein L17	Mitochondrial ribosomal protein S9	0.999
MRPL17	MRRF	ENSP00000288937	ENSP00000343867	Mitochondrial ribosomal protein L17	Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)	0.985
MRPL17	MTRF1L	ENSP00000288937	ENSP00000356202	Mitochondrial ribosomal protein L17	Peptide chain release factor 1-like, mitochondrial; Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG	0.976

page 1 of 6

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2020

Credits

Access

Info

About