node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDH16A1 | ETNK2 | ENSP00000293350 | ENSP00000356169 | Aldehyde dehydrogenase 16 family member A1 | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | 0.666 |
ALDH16A1 | GOLT1A | ENSP00000293350 | ENSP00000308535 | Aldehyde dehydrogenase 16 family member A1 | Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | 0.678 |
ALDH16A1 | GYS2 | ENSP00000293350 | ENSP00000261195 | Aldehyde dehydrogenase 16 family member A1 | Glycogen [starch] synthase, liver; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Glycosyl transferases group 1 domain containing | 0.736 |
ALDH16A1 | PIH1D1 | ENSP00000293350 | ENSP00000262265 | Aldehyde dehydrogenase 16 family member A1 | PIH1 domain-containing protein 1; Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles. Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription. Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1. Positively regulates the assembly and activity of the mTORC1 complex; Belongs to the PIH1 family | 0.806 |
ALDH16A1 | PIK3C2B | ENSP00000293350 | ENSP00000356155 | Aldehyde dehydrogenase 16 family member A1 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns. Does not phosphorylate PtdIns(4,5)P2. May be involved in EGF and PDGF signaling cascades; Belongs to the PI3/PI4-kinase family | 0.629 |
ALDH16A1 | PLEKHA6 | ENSP00000293350 | ENSP00000272203 | Aldehyde dehydrogenase 16 family member A1 | Pleckstrin homology domain containing A6 | 0.708 |
ETNK2 | ALDH16A1 | ENSP00000356169 | ENSP00000293350 | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | Aldehyde dehydrogenase 16 family member A1 | 0.666 |
ETNK2 | ETNPPL | ENSP00000356169 | ENSP00000296486 | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | Ethanolamine-phosphate phospho-lyase; Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde | 0.907 |
ETNK2 | GOLT1A | ENSP00000356169 | ENSP00000308535 | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | 0.760 |
ETNK2 | GPCPD1 | ENSP00000356169 | ENSP00000368305 | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | Glycerophosphocholine phosphodiesterase GPCPD1; May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity; Belongs to the glycerophosphoryl diester phosphodiesterase family | 0.912 |
ETNK2 | GYS2 | ENSP00000356169 | ENSP00000261195 | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | Glycogen [starch] synthase, liver; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Glycosyl transferases group 1 domain containing | 0.733 |
ETNK2 | PCYT2 | ENSP00000356169 | ENSP00000442050 | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP-ethanolamine | 0.975 |
ETNK2 | PIH1D1 | ENSP00000356169 | ENSP00000262265 | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | PIH1 domain-containing protein 1; Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles. Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription. Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1. Positively regulates the assembly and activity of the mTORC1 complex; Belongs to the PIH1 family | 0.703 |
ETNK2 | PIK3C2B | ENSP00000356169 | ENSP00000356155 | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns. Does not phosphorylate PtdIns(4,5)P2. May be involved in EGF and PDGF signaling cascades; Belongs to the PI3/PI4-kinase family | 0.728 |
ETNK2 | PISD | ENSP00000356169 | ENSP00000371586 | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine; Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily | 0.624 |
ETNK2 | PLEKHA6 | ENSP00000356169 | ENSP00000272203 | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | Pleckstrin homology domain containing A6 | 0.731 |
ETNPPL | ETNK2 | ENSP00000296486 | ENSP00000356169 | Ethanolamine-phosphate phospho-lyase; Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | 0.907 |
ETNPPL | PCYT2 | ENSP00000296486 | ENSP00000442050 | Ethanolamine-phosphate phospho-lyase; Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde | Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP-ethanolamine | 0.900 |
GOLT1A | ALDH16A1 | ENSP00000308535 | ENSP00000293350 | Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | Aldehyde dehydrogenase 16 family member A1 | 0.678 |
GOLT1A | ETNK2 | ENSP00000308535 | ENSP00000356169 | Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | 0.760 |