• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF597 ZNF597 PRAP1 PRAP1 C4orf33 C4orf33 TMEM109 TMEM109 ACTL7B ACTL7B CCDC185 CCDC185 SUSD4 SUSD4 RAD21L1 RAD21L1 CCER1 CCER1 TEX19 TEX19 C5orf47 C5orf47
"CCDC185" - Coiled-coil domain containing 185 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CCDC185Coiled-coil domain containing 185 (623 aa)    
Predicted Functional Partners:
C5orf47
Uncharacterized protein C5orf47; Chromosome 5 open reading frame 47 (176 aa)
     
   
  0.771
CCER1
Coiled-coil glutamate rich protein 1 (406 aa)
     
   
  0.722
C4orf33
UPF0462 protein C4orf33; Chromosome 4 open reading frame 33 (199 aa)
           
  0.631
RAD21L1
Double-strand-break repair protein rad21-like protein 1; Meiosis-specific component of some cohesin complex required during the initial steps of prophase I in male meiosis. Probably required during early meiosis in males for separation of sister chromatids and homologous chromosomes. Replaces RAD21 in premeiotic S phase (during early stages of prophase I), while RAD21 reappears in later stages of prophase I. Involved in synaptonemal complex assembly, synapsis initiation and crossover recombination between homologous chromosomes during prophase I (By similarity) (556 aa)
     
   
  0.599
TEX19
Testis-expressed protein 19; Required during spermatogenesis and placenta development, participating in the repression of retrotransposable elements and prevent their mobilization. Collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins. Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence element [...] (164 aa)
           
  0.549
PRAP1
Proline-rich acidic protein 1; May play an important role in maintaining normal growth homeostasis in epithelial cells (151 aa)
           
  0.541
SUSD4
Sushi domain-containing protein 4; Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways; Sushi domain containing (490 aa)
           
  0.527
TMEM109
Transmembrane protein 109; May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death. Can form voltage-gated calcium and potassium channels in vitro (By similarity) (243 aa)
           
  0.527
ACTL7B
Actin-like protein 7B; Actin related proteins; Belongs to the actin family (415 aa)
     
   
  0.508
ZNF597
Zinc finger protein 597; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (424 aa)
           
  0.497
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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