node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALPI | ALPP | ENSP00000295463 | ENSP00000375881 | Alkaline phosphatase, intestinal | Alkaline phosphatase, placental | 0.855 |
ALPI | ALPPL2 | ENSP00000295463 | ENSP00000295453 | Alkaline phosphatase, intestinal | Alkaline phosphatase, placental like 2 | 0.968 |
ALPI | ENTPD1 | ENSP00000295463 | ENSP00000360250 | Alkaline phosphatase, intestinal | Ectonucleoside triphosphate diphosphohydrolase 1; In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well; Belongs to the GDA1/CD39 NTPase family | 0.568 |
ALPI | ENTPD2 | ENSP00000295463 | ENSP00000347213 | Alkaline phosphatase, intestinal | Ectonucleoside triphosphate diphosphohydrolase 2; In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP | 0.617 |
ALPI | ENTPD8 | ENSP00000295463 | ENSP00000360561 | Alkaline phosphatase, intestinal | Ectonucleoside triphosphate diphosphohydrolase 8; Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP | 0.699 |
ALPI | NTPCR | ENSP00000295463 | ENSP00000355587 | Alkaline phosphatase, intestinal | Cancer-related nucleoside-triphosphatase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family | 0.910 |
ALPI | TPK1 | ENSP00000295463 | ENSP00000353165 | Alkaline phosphatase, intestinal | Thiamin pyrophosphokinase 1; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate | 0.901 |
ALPP | ALPI | ENSP00000375881 | ENSP00000295463 | Alkaline phosphatase, placental | Alkaline phosphatase, intestinal | 0.855 |
ALPP | ALPPL2 | ENSP00000375881 | ENSP00000295453 | Alkaline phosphatase, placental | Alkaline phosphatase, placental like 2 | 0.873 |
ALPP | ENTPD1 | ENSP00000375881 | ENSP00000360250 | Alkaline phosphatase, placental | Ectonucleoside triphosphate diphosphohydrolase 1; In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well; Belongs to the GDA1/CD39 NTPase family | 0.545 |
ALPP | ENTPD2 | ENSP00000375881 | ENSP00000347213 | Alkaline phosphatase, placental | Ectonucleoside triphosphate diphosphohydrolase 2; In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP | 0.593 |
ALPP | ENTPD8 | ENSP00000375881 | ENSP00000360561 | Alkaline phosphatase, placental | Ectonucleoside triphosphate diphosphohydrolase 8; Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP | 0.608 |
ALPP | NTPCR | ENSP00000375881 | ENSP00000355587 | Alkaline phosphatase, placental | Cancer-related nucleoside-triphosphatase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family | 0.908 |
ALPP | TPK1 | ENSP00000375881 | ENSP00000353165 | Alkaline phosphatase, placental | Thiamin pyrophosphokinase 1; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate | 0.901 |
ALPPL2 | ALPI | ENSP00000295453 | ENSP00000295463 | Alkaline phosphatase, placental like 2 | Alkaline phosphatase, intestinal | 0.968 |
ALPPL2 | ALPP | ENSP00000295453 | ENSP00000375881 | Alkaline phosphatase, placental like 2 | Alkaline phosphatase, placental | 0.873 |
ALPPL2 | ENTPD1 | ENSP00000295453 | ENSP00000360250 | Alkaline phosphatase, placental like 2 | Ectonucleoside triphosphate diphosphohydrolase 1; In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well; Belongs to the GDA1/CD39 NTPase family | 0.574 |
ALPPL2 | ENTPD2 | ENSP00000295453 | ENSP00000347213 | Alkaline phosphatase, placental like 2 | Ectonucleoside triphosphate diphosphohydrolase 2; In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP | 0.609 |
ALPPL2 | ENTPD8 | ENSP00000295453 | ENSP00000360561 | Alkaline phosphatase, placental like 2 | Ectonucleoside triphosphate diphosphohydrolase 8; Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP | 0.661 |
ALPPL2 | NTPCR | ENSP00000295453 | ENSP00000355587 | Alkaline phosphatase, placental like 2 | Cancer-related nucleoside-triphosphatase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family | 0.910 |