node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CNST | ZNF670 | ENSP00000355470 | ENSP00000355459 | Consortin; Required for targeting of connexins to the plasma membrane; Protein phosphatase 1 regulatory subunits | Zinc finger protein 670; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.444 |
DDX52 | PIGW | ENSP00000479504 | ENSP00000482202 | Probable ATP-dependent RNA helicase DDX52; DExD-box helicase 52; Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity); Belongs to the PIGW family | 0.576 |
DDX52 | TADA2A | ENSP00000479504 | ENSP00000481091 | Probable ATP-dependent RNA helicase DDX52; DExD-box helicase 52; Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily | Transcriptional adapter 2-alpha; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 ’Lys-321’ acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote XRCC6 acetylation thus facilitating cell apoptosis in [...] | 0.614 |
DDX52 | TBC1D3G | ENSP00000479504 | ENSP00000456861 | Probable ATP-dependent RNA helicase DDX52; DExD-box helicase 52; Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily | TBC1 domain family member 3G; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity) | 0.458 |
DDX52 | ZNF670 | ENSP00000479504 | ENSP00000355459 | Probable ATP-dependent RNA helicase DDX52; DExD-box helicase 52; Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily | Zinc finger protein 670; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.422 |
DDX52 | ZNHIT3 | ENSP00000479504 | ENSP00000484687 | Probable ATP-dependent RNA helicase DDX52; DExD-box helicase 52; Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily | Zinc finger HIT-type containing 3 | 0.613 |
ENSG00000274933 | ZNF670 | ENSP00000481258 | ENSP00000355459 | TBC1 domain family member 3I; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity) | Zinc finger protein 670; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.458 |
PIGW | DDX52 | ENSP00000482202 | ENSP00000479504 | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity); Belongs to the PIGW family | Probable ATP-dependent RNA helicase DDX52; DExD-box helicase 52; Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily | 0.576 |
PIGW | TADA2A | ENSP00000482202 | ENSP00000481091 | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity); Belongs to the PIGW family | Transcriptional adapter 2-alpha; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 ’Lys-321’ acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote XRCC6 acetylation thus facilitating cell apoptosis in [...] | 0.627 |
PIGW | TBC1D3G | ENSP00000482202 | ENSP00000456861 | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity); Belongs to the PIGW family | TBC1 domain family member 3G; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity) | 0.486 |
PIGW | TBC1D3H | ENSP00000482202 | ENSP00000482630 | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity); Belongs to the PIGW family | TBC1 domain family member 3H; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity) | 0.526 |
PIGW | ZNF670 | ENSP00000482202 | ENSP00000355459 | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity); Belongs to the PIGW family | Zinc finger protein 670; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.442 |
PIGW | ZNHIT3 | ENSP00000482202 | ENSP00000484687 | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity); Belongs to the PIGW family | Zinc finger HIT-type containing 3 | 0.609 |
SH3BP5L | ZNF670 | ENSP00000355428 | ENSP00000355459 | SH3 binding domain protein 5 like | Zinc finger protein 670; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.560 |
TADA2A | DDX52 | ENSP00000481091 | ENSP00000479504 | Transcriptional adapter 2-alpha; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 ’Lys-321’ acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote XRCC6 acetylation thus facilitating cell apoptosis in [...] | Probable ATP-dependent RNA helicase DDX52; DExD-box helicase 52; Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily | 0.614 |
TADA2A | PIGW | ENSP00000481091 | ENSP00000482202 | Transcriptional adapter 2-alpha; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 ’Lys-321’ acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote XRCC6 acetylation thus facilitating cell apoptosis in [...] | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity); Belongs to the PIGW family | 0.627 |
TADA2A | TBC1D3G | ENSP00000481091 | ENSP00000456861 | Transcriptional adapter 2-alpha; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 ’Lys-321’ acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote XRCC6 acetylation thus facilitating cell apoptosis in [...] | TBC1 domain family member 3G; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity) | 0.499 |
TADA2A | TBC1D3H | ENSP00000481091 | ENSP00000482630 | Transcriptional adapter 2-alpha; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 ’Lys-321’ acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote XRCC6 acetylation thus facilitating cell apoptosis in [...] | TBC1 domain family member 3H; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity) | 0.537 |
TADA2A | ZNF670 | ENSP00000481091 | ENSP00000355459 | Transcriptional adapter 2-alpha; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 ’Lys-321’ acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote XRCC6 acetylation thus facilitating cell apoptosis in [...] | Zinc finger protein 670; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.490 |
TADA2A | ZNHIT3 | ENSP00000481091 | ENSP00000484687 | Transcriptional adapter 2-alpha; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 ’Lys-321’ acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote XRCC6 acetylation thus facilitating cell apoptosis in [...] | Zinc finger HIT-type containing 3 | 0.630 |