node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BZW1 | SH3BP5L | ENSP00000394316 | ENSP00000355428 | Basic leucine zipper and W2 domain-containing protein 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly | SH3 binding domain protein 5 like | 0.532 |
IKZF5 | KIAA1731 | ENSP00000357881 | ENSP00000316681 | Zinc finger protein Pegasus; DNA-binding protein that binds to the 5’GNNTGTNG-3’ core sequence. Transcriptional repressor; Zinc fingers C2H2-type | Centrosomal protein of 295 kDa; Centriole-enriched protein that mediates centriole-to- centrosome conversion at late mitosis, but is dispensable for cartwheel removal or centriole disengagement | 0.489 |
IKZF5 | MON2 | ENSP00000357881 | ENSP00000377250 | Zinc finger protein Pegasus; DNA-binding protein that binds to the 5’GNNTGTNG-3’ core sequence. Transcriptional repressor; Zinc fingers C2H2-type | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | 0.437 |
IKZF5 | SH3BP5L | ENSP00000357881 | ENSP00000355428 | Zinc finger protein Pegasus; DNA-binding protein that binds to the 5’GNNTGTNG-3’ core sequence. Transcriptional repressor; Zinc fingers C2H2-type | SH3 binding domain protein 5 like | 0.548 |
KIAA1731 | IKZF5 | ENSP00000316681 | ENSP00000357881 | Centrosomal protein of 295 kDa; Centriole-enriched protein that mediates centriole-to- centrosome conversion at late mitosis, but is dispensable for cartwheel removal or centriole disengagement | Zinc finger protein Pegasus; DNA-binding protein that binds to the 5’GNNTGTNG-3’ core sequence. Transcriptional repressor; Zinc fingers C2H2-type | 0.489 |
KIAA1731 | MON2 | ENSP00000316681 | ENSP00000377250 | Centrosomal protein of 295 kDa; Centriole-enriched protein that mediates centriole-to- centrosome conversion at late mitosis, but is dispensable for cartwheel removal or centriole disengagement | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | 0.475 |
KIAA1731 | SH3BP5L | ENSP00000316681 | ENSP00000355428 | Centrosomal protein of 295 kDa; Centriole-enriched protein that mediates centriole-to- centrosome conversion at late mitosis, but is dispensable for cartwheel removal or centriole disengagement | SH3 binding domain protein 5 like | 0.572 |
MON2 | IKZF5 | ENSP00000377250 | ENSP00000357881 | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | Zinc finger protein Pegasus; DNA-binding protein that binds to the 5’GNNTGTNG-3’ core sequence. Transcriptional repressor; Zinc fingers C2H2-type | 0.437 |
MON2 | KIAA1731 | ENSP00000377250 | ENSP00000316681 | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | Centrosomal protein of 295 kDa; Centriole-enriched protein that mediates centriole-to- centrosome conversion at late mitosis, but is dispensable for cartwheel removal or centriole disengagement | 0.475 |
MON2 | RAB11A | ENSP00000377250 | ENSP00000261890 | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. T [...] | 0.499 |
MON2 | SH3BP5L | ENSP00000377250 | ENSP00000355428 | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | SH3 binding domain protein 5 like | 0.535 |
PELI3 | SH3BP5L | ENSP00000322532 | ENSP00000355428 | E3 ubiquitin-protein ligase pellino homolog 3; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates ’Lys-63’-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation; Belongs to the pellino family | SH3 binding domain protein 5 like | 0.546 |
RAB11A | MON2 | ENSP00000261890 | ENSP00000377250 | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. T [...] | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | 0.499 |
RAB11A | RAB14 | ENSP00000261890 | ENSP00000362946 | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. T [...] | Ras-related protein Rab-14; Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 s [...] | 0.912 |
RAB11A | SH3BP5L | ENSP00000261890 | ENSP00000355428 | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. T [...] | SH3 binding domain protein 5 like | 0.636 |
RAB14 | RAB11A | ENSP00000362946 | ENSP00000261890 | Ras-related protein Rab-14; Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 s [...] | Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. T [...] | 0.912 |
RAB14 | SH3BP5L | ENSP00000362946 | ENSP00000355428 | Ras-related protein Rab-14; Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 s [...] | SH3 binding domain protein 5 like | 0.537 |
SH3BP5L | BZW1 | ENSP00000355428 | ENSP00000394316 | SH3 binding domain protein 5 like | Basic leucine zipper and W2 domain-containing protein 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly | 0.532 |
SH3BP5L | IKZF5 | ENSP00000355428 | ENSP00000357881 | SH3 binding domain protein 5 like | Zinc finger protein Pegasus; DNA-binding protein that binds to the 5’GNNTGTNG-3’ core sequence. Transcriptional repressor; Zinc fingers C2H2-type | 0.548 |
SH3BP5L | KIAA1731 | ENSP00000355428 | ENSP00000316681 | SH3 binding domain protein 5 like | Centrosomal protein of 295 kDa; Centriole-enriched protein that mediates centriole-to- centrosome conversion at late mitosis, but is dispensable for cartwheel removal or centriole disengagement | 0.572 |