• Version:
  • 11.0 [archived version]
STRINGSTRING
CEP104 CEP104 LRRC47 LRRC47 CCDC27 CCDC27 WRAP73 WRAP73 MEGF6 MEGF6 C1orf174 C1orf174 HAGHL HAGHL ACTRT2 ACTRT2 KIAA2026 KIAA2026 CSRNP2 CSRNP2 OSER1 OSER1
"C1orf174" - UPF0688 protein C1orf174 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
C1orf174UPF0688 protein C1orf174; Chromosome 1 open reading frame 174; Belongs to the UPF0688 family (243 aa)    
Predicted Functional Partners:
CCDC27
Coiled-coil domain containing 27 (656 aa)
           
  0.735
LRRC47
Leucine-rich repeat-containing protein 47; Leucine rich repeat containing 47 (583 aa)
     
   
  0.700
CEP104
Centrosomal protein of 104 kDa; Required for ciliogenesis and for structural integrity at the ciliary tip (925 aa)
           
  0.642
HAGHL
Hydroxyacylglutathione hydrolase-like protein; Hydrolase acting on ester bonds (282 aa)
           
  0.587
KIAA2026
Uncharacterized protein KIAA2026; KIAA2026 (2103 aa)
           
  0.571
ACTRT2
Actin related protein T2 (377 aa)
           
  0.557
CSRNP2
Cysteine/serine-rich nuclear protein 2; Binds to the consensus sequence 5’-AGAGTG-3’ and has transcriptional activator activity (By similarity). May play a role in apoptosis; Protein phosphatase 1 regulatory subunits (543 aa)
           
  0.556
WRAP73
WD repeat-containing protein WRAP73; The SSX2IP-WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP, CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97-CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal bo [...] (460 aa)
           
  0.532
OSER1
Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 (292 aa)
           
  0.530
MEGF6
Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6 (1541 aa)
           
  0.515
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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