C19orf45 protein (human) - STRING database

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C19orf45

Testis-expressed protein 45; Chromosome 19 open reading frame 45 (505 aa)

Predicted Functional Partners:

ZNF783

0.669

BPIFB3

0.559

GPR171

0.510

ZNF660

0.443

NAA25

0.443

HELQ

0.442

MLLT6

0.420

CADPS2

0.403

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BPIFB3	C19orf45	ENSP00000364643	ENSP00000355241	BPI fold-containing family B member 3; May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received (By similarity); BPI fold containing	Testis-expressed protein 45; Chromosome 19 open reading frame 45	0.559
C19orf45	BPIFB3	ENSP00000355241	ENSP00000364643	Testis-expressed protein 45; Chromosome 19 open reading frame 45	BPI fold-containing family B member 3; May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received (By similarity); BPI fold containing	0.559
C19orf45	CADPS2	ENSP00000355241	ENSP00000398481	Testis-expressed protein 45; Chromosome 19 open reading frame 45	Calcium-dependent secretion activator 2; Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)- dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity); C2 domain containing	0.403
C19orf45	GPR171	ENSP00000355241	ENSP00000308479	Testis-expressed protein 45; Chromosome 19 open reading frame 45	Probable G-protein coupled receptor 171; Orphan receptor; G protein-coupled receptors, Class A orphans	0.510
C19orf45	HELQ	ENSP00000355241	ENSP00000295488	Testis-expressed protein 45; Chromosome 19 open reading frame 45	Helicase POLQ-like; Single-stranded DNA-dependent ATPase and 5’ to 3’ DNA helicase. Involved in the repair of DNA cross- links and double-strand break (DSB) resistance. Participates in FANCD2-mediated repair. Forms a complex with POLN polymerase that participates in homologous recombination (HR) repair and is essential for cellular protection against DNA cross-links; Belongs to the helicase family. SKI2 subfamily	0.442
C19orf45	MLLT6	ENSP00000355241	ENSP00000479910	Testis-expressed protein 45; Chromosome 19 open reading frame 45	Protein AF-17; MLLT6, PHD finger containing	0.420
C19orf45	NAA25	ENSP00000355241	ENSP00000261745	Testis-expressed protein 45; Chromosome 19 open reading frame 45	N-alpha-acetyltransferase 25, NatB auxiliary subunit; Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp-Glu. May play a role in normal cell-cycle progression; Belongs to the MDM20/NAA25 family	0.443
C19orf45	ZNF660	ENSP00000355241	ENSP00000324605	Testis-expressed protein 45; Chromosome 19 open reading frame 45	Zinc finger protein 660; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.443
C19orf45	ZNF783	ENSP00000355241	ENSP00000410890	Testis-expressed protein 45; Chromosome 19 open reading frame 45	Protein ZNF783; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.669
CADPS2	C19orf45	ENSP00000398481	ENSP00000355241	Calcium-dependent secretion activator 2; Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)- dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity); C2 domain containing	Testis-expressed protein 45; Chromosome 19 open reading frame 45	0.403
GPR171	C19orf45	ENSP00000308479	ENSP00000355241	Probable G-protein coupled receptor 171; Orphan receptor; G protein-coupled receptors, Class A orphans	Testis-expressed protein 45; Chromosome 19 open reading frame 45	0.510
HELQ	C19orf45	ENSP00000295488	ENSP00000355241	Helicase POLQ-like; Single-stranded DNA-dependent ATPase and 5’ to 3’ DNA helicase. Involved in the repair of DNA cross- links and double-strand break (DSB) resistance. Participates in FANCD2-mediated repair. Forms a complex with POLN polymerase that participates in homologous recombination (HR) repair and is essential for cellular protection against DNA cross-links; Belongs to the helicase family. SKI2 subfamily	Testis-expressed protein 45; Chromosome 19 open reading frame 45	0.442
MLLT6	C19orf45	ENSP00000479910	ENSP00000355241	Protein AF-17; MLLT6, PHD finger containing	Testis-expressed protein 45; Chromosome 19 open reading frame 45	0.420
MLLT6	ZNF783	ENSP00000479910	ENSP00000410890	Protein AF-17; MLLT6, PHD finger containing	Protein ZNF783; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.405
NAA25	C19orf45	ENSP00000261745	ENSP00000355241	N-alpha-acetyltransferase 25, NatB auxiliary subunit; Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp-Glu. May play a role in normal cell-cycle progression; Belongs to the MDM20/NAA25 family	Testis-expressed protein 45; Chromosome 19 open reading frame 45	0.443
ZNF660	C19orf45	ENSP00000324605	ENSP00000355241	Zinc finger protein 660; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Testis-expressed protein 45; Chromosome 19 open reading frame 45	0.443
ZNF783	C19orf45	ENSP00000410890	ENSP00000355241	Protein ZNF783; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Testis-expressed protein 45; Chromosome 19 open reading frame 45	0.669
ZNF783	MLLT6	ENSP00000410890	ENSP00000479910	Protein ZNF783; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Protein AF-17; MLLT6, PHD finger containing	0.405

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