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  • 11.0 [archived version]
STRINGSTRING
COL6A3 COL6A3 COL5A2 COL5A2 COL6A6 COL6A6 COL5A1 COL5A1 COL6A1 COL6A1 COL2A1 COL2A1 COL1A1 COL1A1 COL6A2 COL6A2 COL3A1 COL3A1 DCN DCN COL1A2 COL1A2
"COL6A1" - Collagen alpha-1(VI) chain in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL6A1Collagen alpha-1(VI) chain; Collagen VI acts as a cell-binding protein; Belongs to the type VI collagen family (1028 aa)    
Predicted Functional Partners:
COL6A2
Collagen alpha-2(VI) chain; Collagen VI acts as a cell-binding protein; Collagens (1019 aa)
      
 
0.996
COL1A1
Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Collagens (1464 aa)
      
 
0.994
COL3A1
Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12 (1466 aa)
      
 
0.991
COL6A3
Collagen alpha-3(VI) chain; Collagen VI acts as a cell-binding protein; Collagens (3177 aa)
      
 
0.990
COL1A2
Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family (1366 aa)
      
 
0.989
COL5A1
Collagen alpha-1(V) chain; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin; Collagens (1838 aa)
      
0.988
COL5A2
Collagen alpha-2(V) chain; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue- specific matrices (By similarity) (1499 aa)
      
 
0.962
DCN
Decorin; May affect the rate of fibrils formation; Small leucine rich repeat proteoglycans (359 aa)
      
  0.960
COL6A6
Collagen alpha-6(VI) chain; Collagen VI acts as a cell-binding protein; Collagens (2263 aa)
      
 
0.960
COL2A1
Collagen alpha-1(II) chain; Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces (1487 aa)
      
0.950
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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