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STRINGSTRING
ANKRD36 ANKRD36 CNNM3 CNNM3 CIAO1 CIAO1 FAHD2A FAHD2A ANKRD39 ANKRD39 FAHD2B FAHD2B FAM178B FAM178B ITPRIPL1 ITPRIPL1 TMEM127 TMEM127 SNRNP200 SNRNP200 NCAPH NCAPH
"ITPRIPL1" - Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
ITPRIPL1Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1 (563 aa)    
Predicted Functional Partners:
NCAPH
Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (741 aa)
  
 
   
  0.800
CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family (339 aa)
            
  0.711
FAHD2B
Fumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity (314 aa)
            
  0.671
FAM178B
Protein FAM178B; Family with sequence similarity 178 member B (679 aa)
            
  0.669
ANKRD39
Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family (183 aa)
            
  0.644
ANKRD36
Ankyrin repeat domain-containing protein 36A; Ankyrin repeat domain containing (1941 aa)
            
  0.587
CNNM3
Metal transporter CNNM3; Probable metal transporter; Belongs to the ACDP family (707 aa)
            
  0.584
TMEM127
Transmembrane protein 127; Controls cell proliferation acting as a negative regulator of TOR signaling pathway mediated by mTORC1. May act as a tumor suppressor (238 aa)
            
  0.581
SNRNP200
U5 small nuclear ribonucleoprotein 200 kDa helicase; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome. Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome (2136 aa)
            
  0.571
FAHD2A
Fumarylacetoacetate hydrolase domain-containing protein 2A; May have hydrolase activity (314 aa)
            
  0.550
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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