• Version:
  • 11.0 [archived version]
STRINGSTRING
ZBED9 ZBED9 ZKSCAN3 ZKSCAN3 ZKSCAN4 ZKSCAN4 ZSCAN22 ZSCAN22 ZNF397 ZNF397 ZNF174 ZNF174 ZSCAN20 ZSCAN20 KNDC1 KNDC1 SCAND1 SCAND1 ZNF394 ZNF394 FAM83E FAM83E
"ZSCAN20" - Zinc finger and SCAN domain-containing protein 20 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
ZSCAN20Zinc finger and SCAN domain-containing protein 20; May be involved in transcriptional regulation; Myb/SANT domain containing (1043 aa)    
Predicted Functional Partners:
ZNF397
Zinc finger protein 397; Isoform 3 acts as a DNA-dependent transcriptional repressor; SCAN domain containing (534 aa)
       
   
0.803
ZNF174
Zinc finger protein 174; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family (407 aa)
       
   
0.775
ZNF394
Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (561 aa)
       
   
0.764
ZKSCAN3
Zinc finger protein with KRAB and SCAN domains 3; Transcriptional factor that binds to the consensus sequence 5’-[GT][AG][AGT]GGGG-3’ and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas; SCAN domain containing (538 aa)
       
   
0.742
ZBED9
SCAN domain-containing protein 3; Zinc finger BED-type containing 9; SCAN domain containing (1325 aa)
     
   
0.740
ZKSCAN4
Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family (545 aa)
       
   
0.729
ZSCAN22
Zinc finger and SCAN domain-containing protein 22; May be involved in transcriptional regulation; SCAN domain containing (491 aa)
       
   
0.729
FAM83E
Protein FAM83E; May play a role in MAPK signaling (478 aa)
           
  0.725
KNDC1
Protein very KIND; RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity). May be involved in cellular senescence (1749 aa)
           
  0.723
SCAND1
SCAN domain-containing protein 1; May regulate transcriptional activity; SCAN domain containing (179 aa)
       
   
0.722
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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