node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKMY2 | METTL13 | ENSP00000303570 | ENSP00000354920 | Ankyrin repeat and MYND domain-containing protein 2; May be involved in the trafficking of signaling proteins to the cilia; Ankyrin repeat domain containing | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | 0.869 |
METTL10 | METTL13 | ENSP00000357829 | ENSP00000354920 | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | 0.782 |
METTL10 | METTL20 | ENSP00000357829 | ENSP00000350353 | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | Electron transfer flavoprotein beta subunit lysine methyltransferase; Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain | 0.811 |
METTL10 | NDUFAF5 | ENSP00000357829 | ENSP00000367346 | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | Arginine-hydroxylase NDUFAF5, mitochondrial; Arginine hydroxylase involved in the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages. Acts by mediating hydroxylation of ’Arg-111’ of NDUFS7. May also have methyltransferase activity (Probable) | 0.735 |
METTL10 | NDUFAF7 | ENSP00000357829 | ENSP00000002125 | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | Protein arginine methyltransferase NDUFAF7, mitochondrial; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Acts by mediating symmetric dimethylation of ’Arg-118’ of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex; Belongs to the NDUFAF7 family | 0.782 |
METTL13 | ANKMY2 | ENSP00000354920 | ENSP00000303570 | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | Ankyrin repeat and MYND domain-containing protein 2; May be involved in the trafficking of signaling proteins to the cilia; Ankyrin repeat domain containing | 0.869 |
METTL13 | METTL10 | ENSP00000354920 | ENSP00000357829 | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | 0.782 |
METTL13 | METTL20 | ENSP00000354920 | ENSP00000350353 | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | Electron transfer flavoprotein beta subunit lysine methyltransferase; Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain | 0.697 |
METTL13 | NDUFAF5 | ENSP00000354920 | ENSP00000367346 | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | Arginine-hydroxylase NDUFAF5, mitochondrial; Arginine hydroxylase involved in the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages. Acts by mediating hydroxylation of ’Arg-111’ of NDUFS7. May also have methyltransferase activity (Probable) | 0.700 |
METTL13 | NDUFAF7 | ENSP00000354920 | ENSP00000002125 | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | Protein arginine methyltransferase NDUFAF7, mitochondrial; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Acts by mediating symmetric dimethylation of ’Arg-118’ of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex; Belongs to the NDUFAF7 family | 0.733 |
METTL13 | PIGC | ENSP00000354920 | ENSP00000356702 | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis | 0.677 |
METTL13 | PPAPDC2 | ENSP00000354920 | ENSP00000371307 | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | Phospholipid phosphatase 6; Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid | 0.705 |
METTL13 | PRRC2C | ENSP00000354920 | ENSP00000343629 | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | Protein PRRC2C; Proline rich coiled-coil 2C | 0.714 |
METTL13 | SUCO | ENSP00000354920 | ENSP00000356696 | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | SUN domain-containing ossification factor; Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation (By similarity) | 0.684 |
METTL13 | TPT1 | ENSP00000354920 | ENSP00000477781 | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | Translationally-controlled tumor protein; Involved in calcium binding and microtubule stabilization | 0.713 |
METTL20 | METTL10 | ENSP00000350353 | ENSP00000357829 | Electron transfer flavoprotein beta subunit lysine methyltransferase; Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | 0.811 |
METTL20 | METTL13 | ENSP00000350353 | ENSP00000354920 | Electron transfer flavoprotein beta subunit lysine methyltransferase; Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain | Methyltransferase-like protein 13; Methyltransferase like 13; Belongs to the methyltransferase superfamily | 0.697 |
METTL20 | NDUFAF5 | ENSP00000350353 | ENSP00000367346 | Electron transfer flavoprotein beta subunit lysine methyltransferase; Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain | Arginine-hydroxylase NDUFAF5, mitochondrial; Arginine hydroxylase involved in the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages. Acts by mediating hydroxylation of ’Arg-111’ of NDUFS7. May also have methyltransferase activity (Probable) | 0.735 |
METTL20 | NDUFAF7 | ENSP00000350353 | ENSP00000002125 | Electron transfer flavoprotein beta subunit lysine methyltransferase; Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain | Protein arginine methyltransferase NDUFAF7, mitochondrial; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Acts by mediating symmetric dimethylation of ’Arg-118’ of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex; Belongs to the NDUFAF7 family | 0.843 |
NDUFAF5 | METTL10 | ENSP00000367346 | ENSP00000357829 | Arginine-hydroxylase NDUFAF5, mitochondrial; Arginine hydroxylase involved in the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages. Acts by mediating hydroxylation of ’Arg-111’ of NDUFS7. May also have methyltransferase activity (Probable) | EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-318’ | 0.735 |