https://version11.string-db.org/cgi/show_network_section.pl?networkId=RNVK8pcUh2MP
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[archived version]
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There are several matches for 'ENSP00000354896'.
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organism
protein
Homo sapiens
CD247 - T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of do [...]
[a.k.a. TCRZ, T3Z, CD3Z,
ENSP00000354896
]
Homo sapiens
GRM1 - Metabotropic glutamate receptor 1; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum
[a.k.a. GPRC1A, MGLUR1, L76627,
ENSP00000354896
]