| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADCK2 | BRWD1 | ENSP00000072869 | ENSP00000330753 | Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) | Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Bromodomain containing | 0.441 |
| ADCK2 | NUDCD1 | ENSP00000072869 | ENSP00000239690 | Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) | NudC domain containing 1 | 0.516 |
| ADCK2 | ZNF627 | ENSP00000072869 | ENSP00000354414 | Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) | Zinc finger protein 627; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.429 |
| BRWD1 | ADCK2 | ENSP00000330753 | ENSP00000072869 | Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Bromodomain containing | Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) | 0.441 |
| BRWD1 | NUDCD1 | ENSP00000330753 | ENSP00000239690 | Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Bromodomain containing | NudC domain containing 1 | 0.400 |
| BRWD1 | ZNF627 | ENSP00000330753 | ENSP00000354414 | Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Bromodomain containing | Zinc finger protein 627; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.402 |
| NUDCD1 | ADCK2 | ENSP00000239690 | ENSP00000072869 | NudC domain containing 1 | Uncharacterized aarF domain-containing protein kinase 2; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) | 0.516 |
| NUDCD1 | BRWD1 | ENSP00000239690 | ENSP00000330753 | NudC domain containing 1 | Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Bromodomain containing | 0.400 |
| NUDCD1 | ZNF627 | ENSP00000239690 | ENSP00000354414 | NudC domain containing 1 | Zinc finger protein 627; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.440 |
| OR13G1 | ROS1 | ENSP00000352717 | ENSP00000357494 | Olfactory receptor 13G1; Odorant receptor; Olfactory receptors, family 13 | Proto-oncogene tyrosine-protein kinase ROS; Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation [...] | 0.906 |
| OR13G1 | TAS2R50 | ENSP00000352717 | ENSP00000424040 | Olfactory receptor 13G1; Odorant receptor; Olfactory receptors, family 13 | Taste receptor type 2 member 50; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity); Belongs to the G-protein coupled receptor T2R family | 0.930 |
| OR13G1 | ZNF627 | ENSP00000352717 | ENSP00000354414 | Olfactory receptor 13G1; Odorant receptor; Olfactory receptors, family 13 | Zinc finger protein 627; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.680 |
| ROS1 | OR13G1 | ENSP00000357494 | ENSP00000352717 | Proto-oncogene tyrosine-protein kinase ROS; Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation [...] | Olfactory receptor 13G1; Odorant receptor; Olfactory receptors, family 13 | 0.906 |
| ROS1 | TAS2R50 | ENSP00000357494 | ENSP00000424040 | Proto-oncogene tyrosine-protein kinase ROS; Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation [...] | Taste receptor type 2 member 50; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity); Belongs to the G-protein coupled receptor T2R family | 0.905 |
| ROS1 | ZNF627 | ENSP00000357494 | ENSP00000354414 | Proto-oncogene tyrosine-protein kinase ROS; Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation [...] | Zinc finger protein 627; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.472 |
| TAS2R50 | OR13G1 | ENSP00000424040 | ENSP00000352717 | Taste receptor type 2 member 50; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity); Belongs to the G-protein coupled receptor T2R family | Olfactory receptor 13G1; Odorant receptor; Olfactory receptors, family 13 | 0.930 |
| TAS2R50 | ROS1 | ENSP00000424040 | ENSP00000357494 | Taste receptor type 2 member 50; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity); Belongs to the G-protein coupled receptor T2R family | Proto-oncogene tyrosine-protein kinase ROS; Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation [...] | 0.905 |
| TAS2R50 | ZNF627 | ENSP00000424040 | ENSP00000354414 | Taste receptor type 2 member 50; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity); Belongs to the G-protein coupled receptor T2R family | Zinc finger protein 627; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.670 |
| TRIM28 | ZNF627 | ENSP00000253024 | ENSP00000354414 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 627; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.913 |
| ZNF608 | ZNF627 | ENSP00000307746 | ENSP00000354414 | Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription; Zinc fingers C2H2-type | Zinc finger protein 627; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.572 |
