node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKDD1A | CCDC135 | ENSP00000325895 | ENSP00000353942 | Ankyrin repeat and death domain containing 1A | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | 0.750 |
ANKDD1A | HMHA1 | ENSP00000325895 | ENSP00000439601 | Ankyrin repeat and death domain containing 1A | Rho GTPase-activating protein 45; Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity | 0.683 |
ANKDD1A | SAMD10 | ENSP00000325895 | ENSP00000358902 | Ankyrin repeat and death domain containing 1A | Sterile alpha motif domain containing 10 | 0.726 |
ANKDD1A | SOWAHD | ENSP00000325895 | ENSP00000340975 | Ankyrin repeat and death domain containing 1A | Ankyrin repeat domain-containing protein SOWAHD; Sosondowah ankyrin repeat domain family member D; Belongs to the SOWAH family | 0.756 |
ANKDD1A | TAGAP | ENSP00000325895 | ENSP00000356033 | Ankyrin repeat and death domain containing 1A | T-cell activation Rho GTPase-activating protein; May function as a GTPase-activating protein and may play important roles during T-cell activation | 0.704 |
CCDC135 | ANKDD1A | ENSP00000353942 | ENSP00000325895 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | Ankyrin repeat and death domain containing 1A | 0.750 |
CCDC135 | GAS8 | ENSP00000353942 | ENSP00000268699 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | 0.719 |
CCDC135 | HMHA1 | ENSP00000353942 | ENSP00000439601 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | Rho GTPase-activating protein 45; Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity | 0.653 |
CCDC135 | IQCA1 | ENSP00000353942 | ENSP00000407213 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | IQ motif containing with AAA domain 1 | 0.702 |
CCDC135 | IQCD | ENSP00000353942 | ENSP00000299732 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | IQ domain-containing protein D; Cilia and flagella associated | 0.753 |
CCDC135 | MDN1 | ENSP00000353942 | ENSP00000358400 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits. Functions at successive maturation steps to remove ribosomal factors at critical transition points, first driving the exit of early pre- 60S particles from the nucleolus and then driving late pre-60S particles from the nucleus (By similarity). At an early stage in 60S maturation, mediates the dissociation of the PeBoW complex (PES1-BOP1-WDR12) from early pre-60S particles, rendering them competent for export from the nucleolus to the nucleoplasm (By similarity). Subsequently recruited to [...] | 0.648 |
CCDC135 | SAMD10 | ENSP00000353942 | ENSP00000358902 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | Sterile alpha motif domain containing 10 | 0.648 |
CCDC135 | SOWAHD | ENSP00000353942 | ENSP00000340975 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | Ankyrin repeat domain-containing protein SOWAHD; Sosondowah ankyrin repeat domain family member D; Belongs to the SOWAH family | 0.682 |
CCDC135 | TAGAP | ENSP00000353942 | ENSP00000356033 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | T-cell activation Rho GTPase-activating protein; May function as a GTPase-activating protein and may play important roles during T-cell activation | 0.688 |
CCDC135 | TCTE1 | ENSP00000353942 | ENSP00000360560 | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.680 |
GAS8 | CCDC135 | ENSP00000268699 | ENSP00000353942 | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family | 0.719 |
GAS8 | IQCA1 | ENSP00000268699 | ENSP00000407213 | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | IQ motif containing with AAA domain 1 | 0.664 |
GAS8 | IQCD | ENSP00000268699 | ENSP00000299732 | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | IQ domain-containing protein D; Cilia and flagella associated | 0.512 |
GAS8 | TCTE1 | ENSP00000268699 | ENSP00000360560 | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | T-complex-associated-testis-expressed 1; Dynein regulatory complex | 0.677 |
HMHA1 | ANKDD1A | ENSP00000439601 | ENSP00000325895 | Rho GTPase-activating protein 45; Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity | Ankyrin repeat and death domain containing 1A | 0.683 |