PCMTD1 protein (human) - STRING database

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PCMTD1

protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family (357 aa)

Predicted Functional Partners:

CACFD1

0.801

PLEKHA7

0.789

SLC25A32

0.681

COL11A1

0.675

MAPRE1

0.673

FER1L6

0.667

PUS7

0.634

ACAD10

0.588

CCDC126

0.578

CCDC42

0.543

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAD10	FER1L6	ENSP00000389813	ENSP00000428280	Acyl-CoA dehydrogenase family member 10; Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA	Fer-1-like protein 6; Fer-1 like family member 6	0.488
ACAD10	PCMTD1	ENSP00000389813	ENSP00000353739	Acyl-CoA dehydrogenase family member 10; Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	0.588
CACFD1	MAPRE1	ENSP00000440832	ENSP00000364721	Calcium channel flower domain containing 1	Microtubule-associated protein RP/EB family member 1; Plus-end tracking protein (+TIP) that binds to the plus- end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization- interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, [...]	0.712
CACFD1	PCMTD1	ENSP00000440832	ENSP00000353739	Calcium channel flower domain containing 1	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	0.801
CCDC126	PCMTD1	ENSP00000304355	ENSP00000353739	Coiled-coil domain containing 126	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	0.578
CCDC42	PCMTD1	ENSP00000293845	ENSP00000353739	Coiled-coil domain-containing protein 42; Required for sperm development	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	0.543
COL11A1	PCMTD1	ENSP00000359114	ENSP00000353739	Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils; Collagens	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	0.675
COL11A1	PLEKHA7	ENSP00000359114	ENSP00000347883	Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils; Collagens	Pleckstrin homology domain-containing family A member 7; Required for zonula adherens biogenesis and maintenance. Acts via its interaction with KIAA1543/Nezha, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site; Pleckstrin homology domain containing	0.649
FER1L6	ACAD10	ENSP00000428280	ENSP00000389813	Fer-1-like protein 6; Fer-1 like family member 6	Acyl-CoA dehydrogenase family member 10; Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA	0.488
FER1L6	PCMTD1	ENSP00000428280	ENSP00000353739	Fer-1-like protein 6; Fer-1 like family member 6	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	0.667
MAPRE1	CACFD1	ENSP00000364721	ENSP00000440832	Microtubule-associated protein RP/EB family member 1; Plus-end tracking protein (+TIP) that binds to the plus- end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization- interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, [...]	Calcium channel flower domain containing 1	0.712
MAPRE1	PCMTD1	ENSP00000364721	ENSP00000353739	Microtubule-associated protein RP/EB family member 1; Plus-end tracking protein (+TIP) that binds to the plus- end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization- interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, [...]	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	0.673
PCMTD1	ACAD10	ENSP00000353739	ENSP00000389813	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	Acyl-CoA dehydrogenase family member 10; Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA	0.588
PCMTD1	CACFD1	ENSP00000353739	ENSP00000440832	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	Calcium channel flower domain containing 1	0.801
PCMTD1	CCDC126	ENSP00000353739	ENSP00000304355	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	Coiled-coil domain containing 126	0.578
PCMTD1	CCDC42	ENSP00000353739	ENSP00000293845	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	Coiled-coil domain-containing protein 42; Required for sperm development	0.543
PCMTD1	COL11A1	ENSP00000353739	ENSP00000359114	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	Collagen alpha-1(XI) chain; May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils; Collagens	0.675
PCMTD1	FER1L6	ENSP00000353739	ENSP00000428280	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	Fer-1-like protein 6; Fer-1 like family member 6	0.667
PCMTD1	MAPRE1	ENSP00000353739	ENSP00000364721	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	Microtubule-associated protein RP/EB family member 1; Plus-end tracking protein (+TIP) that binds to the plus- end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization- interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, [...]	0.673
PCMTD1	PLEKHA7	ENSP00000353739	ENSP00000347883	protein-L-isoaspartate O-methyltransferase domain containing 1; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family	Pleckstrin homology domain-containing family A member 7; Required for zonula adherens biogenesis and maintenance. Acts via its interaction with KIAA1543/Nezha, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site; Pleckstrin homology domain containing	0.789

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