node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC144A | ENSG00000271092 | ENSP00000353717 | ENSP00000475025 | Coiled-coil domain containing 144A | TMEM56-RWDD3 readthrough | 0.542 |
CCDC144A | LPHN1 | ENSP00000353717 | ENSP00000340688 | Coiled-coil domain containing 144A | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | 0.411 |
CCDC144A | SGIP1 | ENSP00000353717 | ENSP00000360076 | Coiled-coil domain containing 144A | SH3-containing GRB2-like protein 3-interacting protein 1; May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis | 0.497 |
CCDC144A | SMC1B | ENSP00000353717 | ENSP00000350036 | Coiled-coil domain containing 144A | Structural maintenance of chromosomes protein 1B; Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, t [...] | 0.416 |
CCDC144A | SMC2 | ENSP00000353717 | ENSP00000286398 | Coiled-coil domain containing 144A | Structural maintenance of chromosomes protein 2; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases; Belongs to the SMC family. SMC2 subfamily | 0.468 |
CCDC144A | TMEM56 | ENSP00000353717 | ENSP00000359222 | Coiled-coil domain containing 144A | Transmembrane protein 56; TLC domain containing | 0.532 |
CCDC144A | TSTA3 | ENSP00000353717 | ENSP00000398803 | Coiled-coil domain containing 144A | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction; Short chain dehydrogenase/reductase superfamily | 0.461 |
CCDC144A | USP32 | ENSP00000353717 | ENSP00000300896 | Coiled-coil domain containing 144A | Ubiquitin specific peptidase 32; Belongs to the peptidase C19 family | 0.522 |
CCDC144A | ZDHHC2 | ENSP00000353717 | ENSP00000262096 | Coiled-coil domain containing 144A | Palmitoyltransferase ZDHHC2; Palmitoyltransferase specific for GAP43 and DLG4/PSD95; Zinc fingers DHHC-type | 0.445 |
ENSG00000271092 | CCDC144A | ENSP00000475025 | ENSP00000353717 | TMEM56-RWDD3 readthrough | Coiled-coil domain containing 144A | 0.542 |
LPHN1 | CCDC144A | ENSP00000340688 | ENSP00000353717 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | Coiled-coil domain containing 144A | 0.411 |
SGIP1 | CCDC144A | ENSP00000360076 | ENSP00000353717 | SH3-containing GRB2-like protein 3-interacting protein 1; May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis | Coiled-coil domain containing 144A | 0.497 |
SMC1B | CCDC144A | ENSP00000350036 | ENSP00000353717 | Structural maintenance of chromosomes protein 1B; Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, t [...] | Coiled-coil domain containing 144A | 0.416 |
SMC1B | SMC2 | ENSP00000350036 | ENSP00000286398 | Structural maintenance of chromosomes protein 1B; Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, t [...] | Structural maintenance of chromosomes protein 2; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases; Belongs to the SMC family. SMC2 subfamily | 0.784 |
SMC2 | CCDC144A | ENSP00000286398 | ENSP00000353717 | Structural maintenance of chromosomes protein 2; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases; Belongs to the SMC family. SMC2 subfamily | Coiled-coil domain containing 144A | 0.468 |
SMC2 | SMC1B | ENSP00000286398 | ENSP00000350036 | Structural maintenance of chromosomes protein 2; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases; Belongs to the SMC family. SMC2 subfamily | Structural maintenance of chromosomes protein 1B; Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, t [...] | 0.784 |
TMEM56 | CCDC144A | ENSP00000359222 | ENSP00000353717 | Transmembrane protein 56; TLC domain containing | Coiled-coil domain containing 144A | 0.532 |
TSTA3 | CCDC144A | ENSP00000398803 | ENSP00000353717 | GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction; Short chain dehydrogenase/reductase superfamily | Coiled-coil domain containing 144A | 0.461 |
USP32 | CCDC144A | ENSP00000300896 | ENSP00000353717 | Ubiquitin specific peptidase 32; Belongs to the peptidase C19 family | Coiled-coil domain containing 144A | 0.522 |
ZDHHC2 | CCDC144A | ENSP00000262096 | ENSP00000353717 | Palmitoyltransferase ZDHHC2; Palmitoyltransferase specific for GAP43 and DLG4/PSD95; Zinc fingers DHHC-type | Coiled-coil domain containing 144A | 0.445 |